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The efficacy of breast MRI in predicting breast conservation therapy

2006; Wiley; Volume: 94; Issue: 3 Linguagem: Inglês

10.1002/jso.20561

1096-9098

Sarah L. Blair, Michele McElroy, Michael S. Middleton, Chris Comstock, Tanya Wolfson, Mitch Kamrava, Anne M. Wallace, Joanne Mortimer,

Breast Lesions and Carcinomas

Journal of Surgical OncologyVolume 94, Issue 3 p. 220-225 Research Article The efficacy of breast MRI in predicting breast conservation therapy Sarah Blair MD, Corresponding Author Sarah Blair MD slblair@ucsd.edu Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaAssistant Professor of Surgery, 3855 Health Sciences Dr., San Diego, CA 92093-0987. Fax: 858-822-6366.Search for more papers by this authorMichele Mcelroy MD, Michele Mcelroy MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorMichael S. Middleton MD, PhD, Michael S. Middleton MD, PhD Department of Radiology, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorChris Comstock MD, Chris Comstock MD Moore's Cancer Center, University of California San Diego, San Diego, California Department of Radiology, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorTanya Wolfson MA, Tanya Wolfson MA Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorMitch Kamrava MD, Mitch Kamrava MD Department of Family and Preventive Medicine, Division of Biostatistics, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorAnne Wallace MD, Anne Wallace MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorJoanne Mortimer MD, Joanne Mortimer MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this author Sarah Blair MD, Corresponding Author Sarah Blair MD slblair@ucsd.edu Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaAssistant Professor of Surgery, 3855 Health Sciences Dr., San Diego, CA 92093-0987. Fax: 858-822-6366.Search for more papers by this authorMichele Mcelroy MD, Michele Mcelroy MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorMichael S. Middleton MD, PhD, Michael S. Middleton MD, PhD Department of Radiology, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorChris Comstock MD, Chris Comstock MD Moore's Cancer Center, University of California San Diego, San Diego, California Department of Radiology, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorTanya Wolfson MA, Tanya Wolfson MA Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorMitch Kamrava MD, Mitch Kamrava MD Department of Family and Preventive Medicine, Division of Biostatistics, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorAnne Wallace MD, Anne Wallace MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this authorJoanne Mortimer MD, Joanne Mortimer MD Moore's Cancer Center, University of California San Diego, San Diego, CaliforniaSearch for more papers by this author First published: 09 August 2006 https://doi.org/10.1002/jso.20561Citations: 40AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Background Breast conservation therapy (BCT) has equal efficacy compared to mastectomy in treating breast cancer. Accurate pre-operative measurement of tumor size can limit re-excision procedures. Breast MRI may improve pre-operative evaluation of extent of disease. Objective To examine the correlation of extent of disease on breast MRI with pathologic data to determine the utility of breast MRI in surgical planning of BCT. Methods We retrospectively reviewed our prospective database of women undergoing breast MRI. We identified 115 women with breast cancer who underwent a breast MRI and a surgical resection from 2000 to 2003. We compared patients with high-grade tumors (HG, n = 40) to patients with low grade (LG, n = 75). Results The size of the tumor on MRI correlated with the pathologic size for HG tumors (HG R = 0.76 vs. LG R = 0.45, P = 0.033). Mastectomy was performed in 53 patients. In 10 patients with LG tumors, the MRI findings overestimated their disease. In 11 out of 115 patients the primary tumor or a second tumor was only seen by MRI. Conclusion Breast MRI does change surgical management by detecting additional malignancies. Breast MRI is accurate in staging extent of disease in the breast in patients with HG tumors. J. Surg. Oncol. 2006;94:220–225. © 2006 Wiley-Liss, Inc. Citing Literature Volume94, Issue31 September 2006Pages 220-225 RelatedInformation