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Large keratoacanthomas in difficult locations treated with intralesional 5-fiuorouracil

1986; Elsevier BV; Volume: 14; Issue: 5 Linguagem: Inglês

10.1016/s0190-9622(86)70092-3

1097-6787

Colleen M. Parker, C. William Hanke,

Ear and Head Tumors

Keratoacanthoma is a benign tumor; however, it may cause massive destruction of normal tissue during its rapid growth phase. Intralesional 5-fluorouracil (5-FU) has been shown to be an effective treatment for keratoacanthoma. We have successfully treated five patients with large keratoacanthomas in difficult locations. There have been no recurrences during follow-up periods ranging from 18 to 45 months. Intralesional 5-FU may be ineffective for keratoacanthomas that are not rapidly proliferating.