Asymmetric Synthesis of Polyfunctionalized Pyrrolidines from Sulfinimine-Derived Pyrrolidine 2-Phosphonates. Synthesis of Pyrrolidine 225C
2006; American Chemical Society; Volume: 8; Issue: 11 Linguagem: Inglês
10.1021/ol060521c
ISSN1523-7060
AutoresFranklin A. Davis, He Xu, Yongzhong Wu, Junyi Zhang,
Tópico(s)Advanced Synthetic Organic Chemistry
Resumo[reaction: see text] The Horner-Wadsworth-Emmons reaction of aldehydes with sulfinimine-derived 3-oxo pyrrolidine phosphonates represents a new method for the asymmetric synthesis of ring-functionalized cis-2,5-disubstituted 3-oxo pyrrolidines.
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