Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents
2011; American Chemical Society; Volume: 133; Issue: 40 Linguagem: Inglês
10.1021/ja2061159
ISSN1943-2984
AutoresRobert B. P. Elmes, Kim N. Orange, Suzanne M. Cloonan, D. Clive Williams, Thorfinnur Gunnlaugsson,
Tópico(s)Nanocluster Synthesis and Applications
ResumoThe synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h.
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