Anti‐Insect Toxin 5 (Aalts) from Androctonus Australis
1997; Wiley; Volume: 246; Issue: 2 Linguagem: Inglês
10.1111/j.1432-1033.1997.t01-1-00496.x
ISSN1432-1033
AutoresYoshiaki Nakagawa, Young Moo Lee, Elisabeth Lehmberg, R. Herrmann, Revital Herrmann, Haim Moskowitz, A. Daniel Jones, Bruce D. Hammock,
Tópico(s)Insect Resistance and Genetics
ResumoAn insect‐selective scorpion toxin (AaITS) was purified from the venom of the North African scorpion Androctonus australis , and its amino acid sequence was determined by a combination of automated Edman degradation, electrospray‐ionization mass spectrometry, and sequence alignment. This insect toxin is very potent against the tobacco budworm, Heliothis virescens (100% lethal dose < 1.8 μg/100 mg body mass) and shows a distinct insect specificity and various symptoms. It is not toxic to mice after subcutaneous injection. The molecular mass of this toxin is 6882 Da and the amino acid sequence is similar to those of Androctonus australis anti‐insect toxin 4 (AaIT4), Leiurus quinquestriatus depressant anti‐insect toxins (LqhIT2, LqqIT2), and Buthotus judaicus depressant anti‐insect toxin (BJIT2).
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