The familial occurrence of the Kartagener triad in Jamaica
1969; Oxford University Press; Volume: 45; Issue: 529 Linguagem: Inglês
10.1136/pgmj.45.529.736
ISSN1469-0756
Autores Tópico(s)Parasite Biology and Host Interactions
ResumoTHE OCCURRENCE of sinusitis, bronchiectasis and situs inversus in the same patient was first noted by Siewart in 1903.Oeri made similar observations in 1909.However, Kartagener (1933) was the first to conclude that the occurrence of sinusitis and bron- chiectasis was more common in patients with situs inversus than in others.He reported four cases in 1933 and seven cases in 1935 (Kartagener & Hor- lacher, 1935).Since then the triad has acquired his name.Kartagener & Stucki (1962) reviewed 334 reported cases and suggested that the incidence of the syndrome is about 1: 40,000.Gunther (1923) first described a family in which two siblings of four presented with Kartagener's syndrome.Subsequently, at least seven families have been reported.Many authors have found that there is a higher incidence in male than in female siblings (Cockayne, 1938; Logan, Abbott & Hatcher, 1965), that in affected families neither of the parents need show any evidence of the triad, and that features of the syndrome can occur in various combinations within the same family (Bergstrom et al., 1950; Overholt & Bauman, 1958).This report describes a family in which two siblings exhibit the complete Kartagener triad, another sibling showing sinusitis alone.The other three siblings in the family are clinically normal and the parents, who are not consanguinous, show no evi- dence of abnormality or disease (Fig. 1).Case reports Case No. 1
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