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Paradoxical False Memory for Objects After Brain Damage

2010; American Association for the Advancement of Science; Volume: 330; Issue: 6009 Linguagem: Inglês

10.1126/science.1194780

1095-9203

Stephanie M. McTighe, Rosemary A. Cowell, Boyer D. Winters, Timothy J. Bussey, Lisa M. Saksida,

Neural dynamics and brain function

Poor memory after brain damage is usually considered to be a result of information being lost or rendered inaccessible. It is assumed that such memory impairment must be due to the incorrect interpretation of previously encountered information as being novel. In object recognition memory experiments with rats, we found that memory impairment can take the opposite form: a tendency to treat novel experiences as familiar. This impairment could be rescued with the use of a visual-restriction procedure that reduces interference. Such a pattern of data can be explained in terms of a recent representational-hierarchical view of cognition.