Artigo Produção Nacional Revisado por pares

Twenty-three flavonoids from Lonchocarpus subglaucescens

1996; Elsevier BV; Volume: 42; Issue: 5 Linguagem: Inglês

10.1016/0031-9422(96)00134-3

ISSN

1873-3700

Autores

Aderbal F. Magalhães, Ana Maria G.A. Tozzi, Beatriz Helena L. Noronha Sales, Eva G. Magalhães,

Tópico(s)

Morinda citrifolia extract uses

Resumo

Chemical investigation of Lonchocarpus subglaucescens roots resulted in the isolation of 23 flavonoids, whose structures were elucidated by spectroscopic methods. Ponganone III, ovalichromene B, purpurenone, 12α-hydroxyrotenone, (2,3-trans-3,4-trans)-3,4,5,8-tetramethoxy-[2″,3″:7,6]-furanoflavan, 6″,6″-dimethylchromeno- [2″,3″:7,8]-flavone and 3′,4′-methylenedioxy-6″,6″-dimethylchromeno-[2″, 3″:7,8]-flavone had been previously isolated from other sources. The 16 new flavonoids are 6-methoxy-6″,6″-dimethylchromeno-[2″,3″:7,8]-flavanone, (2S)-5,6-dimethoxy-[2″,3″:7,8]-furanoflavanone, (2R,3R)-3,5,6-trimethoxy-[2″,3″,7,8]-furanoflavanonol, 3,4-methylenedioxy-2′-methoxy-6″,6″-dimethylchromeno-[2″,3″:4′,3′]-β-hydroxychalcone, (Z/E)-3,4-methylenedioxy-2′-methoxy-6″,6″-dimethylchromeno-[2″,3″:4′,3′]-9-methoxychalcone, (E)-2′-methoxy-6″,6″-dimethylchromeno-[2″,3″:4′,3′]-9-methoxychalcone, (2,4-cis)-3′,4′-methylenedioxy-4,5,8-trimethoxy-[2″,3″:7,6]-furanoflavan, (2,4-cis)-4,5,6-trimethoxy-[2″,3″:7,8]furanoflavan, 3,4-dimethoxy-2′-hydroxy-6″,6″-dimethylchromeno-[2″,3″:4′,3′]-chalcone, 3,4-methylenedioxy-2′-hydroxy-3′,6′-dimethoxy-[2″,3″:4′,5′]-furanochalcone, (2,3-trans-3,4-cis-3,4,5,6-tetramethoxy-[2″,3″:7,8]-furanoflavan, (2,3-trans-3,4-trans)-3′,4′-methylenedioxy-3,4,5,8-tetramethoxy-[2″,3″:7,6]-furanoflavan, (2,3-trans-3,4-cis)-3′,4′-methylenedioxy-3,4,5,6-tetramethoxy-[2″,3″:7,8]-furanoflavan, 3,4-methylenedioxy-2′-methoxy-[2″,3″:4′,3′]-dihydrochalcone and 3′,4′-methylenedioxy-8-methoxy-5-hydroxy-6″,6″-dimethylchromeno- [2″,3″:7,6]-isoflavone.

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