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Pneumocystis carinii Pneumonia

1966; American College of Physicians; Volume: 65; Issue: 5 Linguagem: Inglês

10.7326/0003-4819-65-5-943

1539-3704

David Rifkind,

Immunodeficiency and Autoimmune Disorders

Article1 November 1966Pneumocystis carinii PneumoniaStudies on the Diagnosis and TreatmentDAVID RIFKIND, PH.D., M.D., TANOUS D. FARIS, M.D., ROLLA B. HILL JR., M.D.DAVID RIFKIND, PH.D., M.D.Search for more papers by this author, TANOUS D. FARIS, M.D.Search for more papers by this author, ROLLA B. HILL JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-5-943 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPneumocystis carinii was first associated in Europe with the syndrome of interstitial plasma cell pneumonia occurring in premature and debilitated infants (1). This infection is now recognized to be of cosmopolitan distribution and to occur also in patients with hematopoietic malignancies (2-4), immunoglobulin defects (5, 6), and in those receiving corticosteroids and cytotoxic drug therapy (7).In a previous communication pneumonia associated with renal transplantation in six patients was described (7). In the single fatal case, autopsy revealed Pneumocystis carinii pneumonia and both pulmonary and disseminated cytomegalovirus infections.This communication summarizes the experience accumulated to date at this Center with...References1. GAJDUSEK DC: Pneumocystis carinii—etiologic agent of interstitial plasma cell pneumonia of premature and young infants. Pediatrics 19: 543, 1957. MedlineGoogle Scholar2. HENDRYPATRICK WSRL: Observations on thirteen cases of Pneumocystis carinii pneumonia. Amer. J. Clin. Path. 38: 401, 1962. CrossrefMedlineGoogle Scholar3. GILBERTFORDHAMBENSON CFCCWR: Death resulting from pneumocystis pneumonia in an adult. 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Deutsch. Med. Wschr. 80: 1357, 1955. CrossrefMedlineGoogle Scholar10. RIFKIND D: Cytomegalovirus infection after renal transplantation. Arch. Intern. Med. (Chicago) 116: 554, 1965. CrossrefMedlineGoogle Scholar11. SHELDON WH: Subclinical pneumocystis pneumonitis. J. Dis. Child. (Chicago) 97: 287, 1959. MedlineGoogle Scholar12. HILLROWLANDSRIFKIND RBDTD: Infectious pulmonary disease in patients receiving immunosuppressive therapy for organ transplantation. New Eng. J. Med. 271. 1021, 1964. CrossrefMedlineGoogle Scholar13. POSTDUTZNASARIAN CWI: Endemic Pneumocystis carinii pneumonia in south Iran. Arch. Dis. Child. 39: 35, 1964. CrossrefMedlineGoogle Scholar14. WATANABECHINCHINIANWEITZMCILVANIE JMHCSK: Pneumocystis carinii pneumonia in a family. JAMA 193: 685, 1965. CrossrefMedlineGoogle Scholar15. LYONSVINIJCHAIKULHENNIGAR HAKGR: Pneumocystis carinii pneumonia unassociated with other disease. Clinical and pathological studies. Arch. Intern. Med. (Chicago) 108: 929, 1961. CrossrefMedlineGoogle Scholar16. KAFTORIBASSANGELLEIGRIFFEL JKHBB: Pneumocystis carinii pneumonia in the adult. Report of a primary case. Arch. Intern. Med. (Chicago) 109: 438, 1962. CrossrefMedlineGoogle Scholar17. HAMBURGERCROSNIERDORMONT JJJ: Experience with 45 renal homotransplantations in man. Lancet 1: 985, 1965. CrossrefMedlineGoogle Scholar18. HAMPERL H: Pneumocystis infection and cytomegaly of the lungs in the newborn and adult. Amer. J. Path. 32: 1, 1956. MedlineGoogle Scholar19. KRAMERCIRONEMOORE RIVCH: Interstitial pneumonia due to Pneumocystis carinii, cytomegalic inclusion disease and hypogammaglobulinemia occurring simultaneously in an infant. A case report with necropsy findings. Pediatrics 29: 816, 1962. MedlineGoogle Scholar20. RIFKINDMARCHIOROWADDELLSTARZL DTLWRTE: Infectious diseases associated with renal homotransplantation. I. Incidence, types and predisposing factors. JAMA 189: 397, 1964. CrossrefMedlineGoogle Scholar21. RIFKINDMARCHIOROWADDELSTARZL DTLWRTE: Infectious diseases associated with renal homotransplantation. II. Differential diagnosis and management. Ibid., p. 402. Google Scholar22. FRENKELGOODSHULTZ JKJTJ: Pathogenesis and chemotherapy of Pneumocystis carinii infection of rats. Progress in Protozoology, Excerpta Medica International Congress Series 91, p. 129, 1965. Google Scholar23. TAN-VINHCOCHARDVU-TRIEU-DONGSOLONAR LAW Diagnostic in vivo de la pneumonie a pneumocystis. Arch. Franc. Pediat. 20: 773, 1963. MedlineGoogle Scholar24. ROBBINSMILLERAREANPEARSON JBRHVMHA: Successful treatment of Pneumocystis carinii pneumonitis in a patient with congenital hypogammaglobulinemia. New Eng. J. Med. 272: 708, 1965. CrossrefMedlineGoogle Scholar25. IVÁDYPÁLDYUNGER GLG: Weitere Erfahrungen bei der Behandlung der interstitiellen plasmacellulären Pneumonie mit Pentamidin. Mschr. Kinderheilk. 111: 297, 1963. MedlineGoogle Scholar26. FRENKELGOODSHULTZ JKJTJ: Cortico-steroid-induced relapse of Pneumocystis infection of rats and its prevention with sulfadiazine-pyrimethamine therapy. Fed. Proc. 24: 614, 1965. Google Scholar27. FRENKELWEBERLUNDE JKRWMN: Acute toxoplasmosis. Effective treatment with pyrimethamine, sulfadiazine, leucovorin calcium, and yeast. JAMA 173: 1471, 1960. CrossrefMedlineGoogle Scholar28. FRENKELGOODSHULTZ JKJTJA: Latent pneumocystis infection of rats, relapse and chemotherapy. Lab. Med. In press. Google Scholar29. GERRARD JW: Pneumocystis pneumonia (letter). Canad. Med. Ass. J. 91: 88, 1964. Google Scholar30. MARSHALLFRENKEL WCJK: Pneumocystis carinii pneumonia(letter). Lancet 1 94, 1966. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, ColoradoFrom the Departments of Medicine, Surgery, and Pathology, University of Colorado Medical Center, and the Veterans Administration Hospital, Denver, Colo.This study was supported in part by grant G-65-37 from the Life Insurance Medical Research Fund, Rosemont, Pa., and grants AM-06283, AM-06344, AI-07319-01, HE-07735, and AM-07772, the U. S. Public Health Service, Washington, D. C.This paper was presented at the 47th Annual Session of the American College of Physicians, New York, N. Y., April 18, 1966.Requests for reprints should be addressed to David Rifkind, M.D., University of Colorado Medical Center, Denver, Colo. 80220. 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POWELL JR., M.D., VINCENT T. DEVITA, M.D.Case 28-1967Systemic fungal infections complicating renal transplantation and immunosuppressive therapyThe Clinical Significance of Cytomegalovirus Infection in Renal Transplant RecipientsDAVID RIFKIND, PH.D., M.D., NEAL GOODMAN, M.D., ROLLA B. HILL JR., M.D.Death after transplantationInfectious diseases. Annual review of significant publications. 1 November 1966Volume 65, Issue 5Page: 943-956KeywordsCytomegalovirus infectionHospital medicinePneumocystisPneumocystis carinii pneumoniaPneumoniaPseudomonas infectionsPulmonary diseasesRenal transplantationResearch fundingSurgery Issue Published: 1 November 1966 PDF DownloadLoading ...