The supratrigeminal region of the rat sends GABA/glycine-cocontaining axon terminals to the motor trigeminal nucleus on the contralateral side
2002; Elsevier BV; Volume: 330; Issue: 1 Linguagem: Inglês
10.1016/s0304-3940(02)00711-5
ISSN1872-7972
AutoresYun-Qing Li, Tao Fasheng, Keiko Okamoto, Sakashi Nomura, Takeshi Kaneko, Noboru Mizuno,
Tópico(s)Ion channel regulation and function
ResumoThe supratrigeminal region (STR), a reticular zone capping the motor trigeminal nucleus (Tm), contains gamma-aminobutyric acid (GABA)ergic and glycinergic neurons which send axons to the contralateral Tm (J. Comp. Neurol. 373 (1996) 498). In the present study we observed that some single synaptic terminals upon Tm motoneurons showed immunoreactivities (IRs) for both glutamic acid decarboxylase (GAD) and glycine transporter 2 (GlyT2). After injecting biotinylated dextran amine (BDA) into the STR, we further observed in the Tm contralateral to the BDA injection that some BDA-labeled axon terminals in close contact with Tm motoneurons showed both GAD- and GlyT2-IRs. Thus, the STR was indicated to send GABAergic/glycinergic axon terminals contralaterally to Tm motoneurons.
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