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BIBTEX RIS

Potentiation of vincristine cytotoxicity by rubiginone B1 and piperafizine A in human moser and K562 cells-Mode of action.

1992; Springer Nature; Volume: 45; Issue: 1 Linguagem: Inglês

10.7164/antibiotics.45.129

ISSN

1881-1469

Autores

Masami Ogasawara, Masami Hasegawa, Yasutaro Hamagishi, Hideo Kamei, TOSHIKAZU OKI,

Tópico(s)

Synthesis and biological activity

Resumo

Rubiginones and piperafizines were isolated from the fermentation broths of Streptomyces griseorubiginosus Q144-21} and Streptoverticillium aspergilloides Q576-22), respectively, in our screening program for potentiators of vincristine (VCR)induced cytotoxicity against human colorectal carcinoma Moser cells in vitro.Among their

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