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Depressive symptoms and Depo-Provera®

1998; Elsevier BV; Volume: 57; Issue: 4 Linguagem: Inglês

10.1016/s0010-7824(98)00024-9

1879-0518

Carolyn Westhoff, Christine J Truman, Debra Kalmuss, Linda F. Cushman, Andrew R. Davidson, Marvin C. Rulin, Stephen Heartwell,

Treatment of Major Depression

Women enrolled in a multicenter prospective study were evaluated to identify any possible relationship between depressive symptoms and the use of contraceptives. Women choosing Depo-Provera® (n = 495) were evaluated before starting these contraceptives and were reinterviewed 1 year later. Women who continued the method had lower depressive symptom scores at baseline than did the women who discontinued the method or who were lost to follow-up. Among the continuing Depo-Provera users, the depressive symptom scores improved slightly at 1 year (7.4 vs 6.7). Those subjects with the highest (ie, worst) scores at enrollment demonstrated improved scores at follow-up.