Psychotic disorders in Argentine patients with refractory temporal lobe epilepsy: A case–control study
2009; Elsevier BV; Volume: 14; Issue: 4 Linguagem: Inglês
10.1016/j.yebeh.2009.02.019
ISSN1525-5069
AutoresLuciana D’Alessio, Brenda Giagante, Cristina Papayannis, Silvia Oddo, Walter Silva, Patricia Solís, Vicente Donnoli, Marcelo Kauffman, D. Consalvo, Luis Marı́a Zieher, Silvia Kochen,
Tópico(s)Pharmacological Effects and Toxicity Studies
ResumoThe issue of psychotic disorders in epilepsy has given rise to great controversy among professionals; however, there are not many studies in this area and the physiopathological mechanisms remain unknown. The aim of this study was to describe the spectrum of psychotic disorders in an Argentine population with refractory temporal lobe epilepsy (RTLE) and to determine the risk factors associated with psychotic disorders. Clinical variables of the epileptic syndrome were compared among a selected population with RTLE with and without psychotic disorders (DSM-IV/Ictal Classification of psychoses). Logistic regression was performed. Sixty-three patients with psychotic disorders (Psychotic Group, PG) and 60 controls (Control Group, CG) were included. The most frequent psychotic disorders were brief psychotic episodes (35%) (DSM-IV) and interictal psychosis (50%) (Ictal Classification). Risk factors for psychotic disorders were bilateral hippocampal sclerosis, history of status epilepticus, and duration of epilepsy greater than 20 years.
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