Isolation and synthesis of 23-methyl-22-dehydrocholesterol -a marine sterol of biosynthetic significance
1979; Elsevier BV; Volume: 20; Issue: 38 Linguagem: Inglês
10.1016/s0040-4039(01)95474-7
ISSN1873-3581
AutoresW. C. M. C. Kokke, Nancy W. Withers, Ian J. Massey, William Fenical, Carl Djerassi,
Tópico(s)Organic Chemistry Cycloaddition Reactions
ResumoAnew sterol, 23-methyl-22-dehydrocholesterol, and several closely relatedsterols, have been isolated from cultures of the dinoflagellat symbiont (zooxanthella) from the marine zoanthid Zoanthus sociatus. The structural features of these sterols suggest that direct bioalkylation of a Δ22 double bond may be a new biosynthetic route to novel sterol side chains.
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