Successful Treatment of Adult Onset Langerhans Cell Histiocytosis with Multi-Drug Combination Therapy
2011; The Japanese Society of Internal Medicine; Volume: 50; Issue: 8 Linguagem: Inglês
10.2169/internalmedicine.50.4808
ISSN1349-7235
AutoresEri Matsuki, Yuiko Tsukada, Aya Nakaya, Kenji Yokoyama, Shinichiro Okamoto,
Tópico(s)Vascular Malformations and Hemangiomas
ResumoAdult onset Langerhans cell histiocytosis (LCH) is a rare disorder. Its clinical features have been well described in children, however remain poorly defined in adults. Optimal treatment strategy is still under debate. We have encountered two cases of adult onset LCH, which obtained a durable disease control by combination chemotherapy using prednisone, vinblastine and 6-mercaptopurine. Herein, we report their clinical features together with a review of the current literature.
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