Revisão Acesso aberto Revisado por pares

Regeneration of vascularized bone

2006; Wiley; Volume: 41; Issue: 1 Linguagem: Inglês

10.1111/j.1600-0757.2006.00158.x

ISSN

1600-0757

Autores

Susan X. Hsiong, David Mooney,

Tópico(s)

Tissue Engineering and Regenerative Medicine

Resumo

Periodontology 2000Volume 41, Issue 1 p. 109-122 Regeneration of vascularized bone Susan X. Hsiong, Susan X. HsiongSearch for more papers by this authorDavid J. Mooney, David J. MooneySearch for more papers by this author Susan X. Hsiong, Susan X. HsiongSearch for more papers by this authorDavid J. Mooney, David J. MooneySearch for more papers by this author First published: 10 May 2006 https://doi.org/10.1111/j.1600-0757.2006.00158.xCitations: 61Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 United States Bone and Joint Decade. Available at: http://www.usbjd.org/index.cfm [accessed on 17 February 2006]. 2 Alam MI, Asahina I, Seto I, Oda M, Enomoto S. Prefabrication of vascularized bone flap induced by recombinant human bone morphogenetic protein 2 (rhBMP-2). Int J Oral Maxillofac Surg 2003: 32: 508–514. 3 Alsberg E, Anderson KW, Albeiruti A, Franceschi RT, Mooney DJ. Cell-interactive alginate hydrogels for bone tissue engineering. J Dent Res 2001: 80: 2025–2029. 4 Alsberg E, Anderson KW, Albeiruti A, Rowley JA, Mooney DJ. Engineering growing tissues. Proc Natl Acad Sci USA 2002: 99: 12025–12030. 5 Alsberg E, Kong HJ, Hirano Y, Smith MK, Albeiruti A, Mooney DJ. Regulating bone formation via controlled scaffold degradation. J Dent Res 2003: 82: 903–908. 6 Ash JD, Overbeek PA. Lens-specific VEGF-A expression induces angioblast migration and proliferation and stimulates angiogenic remodeling. Dev Biol 2000: 223: 383–398. 7 Assmus B, Schachinger V, Teupe C, Britten M, Lehmann R, Dobert N, Grunwald F, Aicher A, Urbich C, Martin H, Hoelzer D, Dimmeler S, Zeiher AM. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002: 106: 3009–3017. 8 Bonadio J, Smiley E, Patil P, Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat Med 1999: 5: 753–759. 9 Bouletreau PJ, Warren SM, Spector JA, Peled ZM, Gerrets RP, Greenwald JA, Longaker MT. Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing. Plast Reconstr Surg 2002: 109: 2384–2397. 10 Braddock M, Houston P, Campbell C, Ashcroft P. Born again bone: tissue engineering for bone repair. News Physiol Sci 2001: 16: 208–213. 11 Caplan AI, Bruder SP. Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. Trends Mol Med 2001: 7: 259–264. 12 Carano RA, Filvaroff EH. Angiogenesis and bone repair. Drug Discov Today 2003: 8: 980–989. 13 Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000: 6: 389–395. 14 Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000: 407: 249–257. 15 Chen RR, Mooney DJ. Polymeric growth factor delivery strategies for tissue engineering. Pharm Res 2003: 20: 1103–1112. 16 Chen D, Zhao M, Harris SE, Mi Z. Signal transduction and biological functions of bone morphogenetic proteins. Front Biosci 2004: 9: 349–358. 17 Cleland JL, Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A. Development of poly-(d,l-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J Control Release 2001: 72: 13–24. 18 Cross MJ, Claesson-Welsh L. FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 2001: 22: 201–207. 19 Danesh-Meyer MJ, Wikesjo UM. Gingival recession defects and guided tissue regeneration: a review. J Periodontal Res 2001: 36: 341–354. 20 DeLise AM, Fischer L, Tuan RS. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 2000: 8: 309–334. 21 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997: 89: 747–754. 22 Ennett AB, Mooney DJ. Tissue engineering strategies for in vivo neovascularisation. Expert Opin Biol Ther 2002: 2: 805–818. 23 Farley J, Dimai HP, Stilt-Coffing B, Farley P, Pham T, Mohan S. Calcitonin increases the concentration of insulin-like growth factors in serum-free cultures of human osteoblast-line cells. Calcif Tissue Int 2000: 67: 247–254. 24 Favus MJ, American Society for Bone and Mineral Research. Primer on the metabolic bone diseases and disorders of mineral metabolism, 4th edn. Philadelphia, PA: Lippincott Williams and Wilkins, 1999. 25 Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003: 9: 669–676. 26 Fittkau MH, Zilla P, Bezuidenhout D, Lutolf MP, Human P, Hubbell JA, Davies N. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides. Biomaterials 2005: 26: 167–174. 27 Gamradt SC, Lieberman JR. Genetic modification of stem cells to enhance bone repair. Ann Biomed Eng 2004: 32: 136–147. 28 Gerber HP, Ferrara N. Angiogenesis and bone growth. Trends Cardiovasc Med 2000: 10: 223–228. 29 Gerstenfeld LC, Cullinane DM, Barnes GL, Graves DT, Einhorn TA. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 2003: 88: 873–884. 30 Goad DL, Rubin J, Wang H, Tashjian AH Jr, Patterson C. Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. Endocrinology 1996: 137: 2262–2268. 31 Goldberg VM, Stevenson S. Natural history of autografts and allografts. Clin Orthop 1987: 7–16. 32 Gu F, Amsden B, Neufeld R. Sustained delivery of vascular endothelial growth factor with alginate beads. J Control Release 2004: 96: 463–472. 33 Gugala Z, Olmsted-Davis EA, Gannon FH, Lindsey RW, Davis AR. Osteoinduction by ex vivo adenovirus-mediated BMP2 delivery is independent of cell type. Gene Ther 2003: 10: 1289–1296. 34 Harris SE, Bonewald LF, Harris MA, Sabatini M, Dallas S, Feng JQ, Ghosh-Choudhury N, Wozney J, Mundy GR. Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts. J Bone Miner Res 1994: 9: 855–863. 35 Harris LD, Kim BS, Mooney DJ. Open pore biodegradable matrices formed with gas foaming. J Biomed Mater Res 1998: 42: 396–402. 36 Harrison D, Johnson R, Tucci M, Puckett A, Tsao A, Hughes J, Benghuzzi H. Interaction of cells with UHMWPE impregnated with the bioactive peptides RGD, RGE or poly-l-lysine. Biomed Sci Instrum 1997: 34: 41–46. 37 Hench LL, Polak JM. Third-generation biomedical materials. Science 2002: 295: 1014–1017. 38 Howard D, Partridge K, Yang X, Clarke NM, Okubo Y, Bessho K, Howdle SM, Shakesheff KM, Oreffo RO. Immunoselection and adenoviral genetic modulation of human osteoprogenitors: in vivo bone formation on PLA scaffold. Biochem Biophys Res Commun 2002: 299: 208–215. 39 Huang YC, Simmons C, Kaigler D, Rice KG, Mooney DJ. Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4). Gene Ther 2005: 12: 418–426. 40 Huang YC, Kaigler D, Rice KG, Krebsbach PH, Mooney DJ. Combined angiogenic and osteogenic factor delivery enhances bone marrow stromal cell-driven bone regeneration. J Bone Miner Res 2005: 20: 848–857. 41 Hutmacher DW. Scaffolds in tissue engineering bone and cartilage. Biomaterials 2000: 21: 2529–2543. 42 Hutmacher D, Hurzeler MB, Schliephake H. A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications. Int J Oral Maxillofac Implants 1996: 11: 667–678. 43 Hutmacher DW, Sittinger M, Risbud MV. Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol 2004: 22: 354–362. 44 Ingber DE, Madri JA, Folkman J. A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution. Endocrinology 1986: 119: 1768–1775. 45 Ishaug SL, Crane GM, Miller MJ, Yasko AW, Yaszemski MJ, Mikos AG. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J Biomed Mater Res 1997: 36: 17–28. 46 Isner JM, Kalka C, Kawamoto A, Asahara T. Bone marrow as a source of endothelial cells for natural and iatrogenic vascular repair. Ann N Y Acad Sci 2001: 953: 75–84. 47 Kaigler D, Krebsbach PH, Polverini PJ, Mooney DJ. Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells. Tissue Eng 2003: 9: 95–103. 48 Kaigler D, Krebsbach PH, West ER, Horger K, Huang YC, Mooney DJ. Endothelial cell modulation of bone marrow stromal cell osteogenic potential. FASEB J 2005: 19: 665–667. 49 Kimoto T, Hosokawa R, Kubo T, Maeda M, Sano A, Akagawa Y. Continuous administration of basic fibroblast growth factor (FGF-2) accelerates bone induction on rat calvaria – an application of a new drug delivery system. J Dent Res 1998: 77: 1965–1969. 50 Krebsbach PH, Gu K, Franceschi RT, Rutherford RB. Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo. Hum Gene Ther 2000: 11: 1201–1210. 51 Kuen Yong Lee EA, Hsiong S, Comisar W, Linderman J, Ziff R, Mooney D. Nanoscale adhesion ligand organization regulates osteoblast proliferation and differentiation. Nanoletters 2004: 4: 1501–1506. 52 Langdahl BL, Kassem M, Moller MK, Eriksen EF. The effects of IGF-I and IGF-II on proliferation and differentiation of human osteoblasts and interactions with growth hormone. Eur J Clin Invest 1998: 28: 176–183. 53 Laurencin CT, Attawia MA, Lu LQ, Borden MD, Lu HH, Gorum WJ, Lieberman JR. Poly(lactide-co-glycolide)/hydroxyapatite delivery of BMP-2-producing cells: a regional gene therapy approach to bone regeneration. Biomaterials 2001: 22: 1271–1277. 54 Leach JK, Mooney DJ. Bone engineering by controlled delivery of osteoinductive molecules and cells. Expert Opin Biol Ther 2004: 4: 1015–1027. 55 Lee KY, Mooney DJ. Hydrogels for tissue engineering. Chem Rev 2001: 101: 1869–1879. 56 LeGeros RZ. Properties of osteoconductive biomaterials: calcium phosphates. Clin Orthop 2002: 81–98. 57 Levenberg S, Golub JS, Amit M, Itskovitz-Eldor J, Langer R. Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 2002: 99: 4391–4396. 58 Li G, Bouxsein ML, Luppen C, Li XJ, Wood M, Seeherman HJ, Wozney JM, Simpson H. Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res 2002: 20: 779–788. 59 Li JZ, Hankins GR, Kao C, Li H, Kammauff J, Helm GA. Osteogenesis in rats induced by a novel recombinant helper-dependent bone morphogenetic protein-9 (BMP-9) adenovirus. J Gene Med 2003: 5: 748–756. 60 Lindahl P, Hellstrom M, Kalen M, Betsholtz C. Endothelial-perivascular cell signaling in vascular development: lessons from knockout mice. Curr Opin Lipidol 1998: 9: 407–411. 61 Linkhart TA, MacCharles DC. Interleukin-1 stimulates release of insulin-like growth factor-I from neonatal mouse calvaria by a prostaglandin synthesis-dependent mechanism. Endocrinology 1992: 131: 2297–2305. 62 Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Muller R, Hubbell JA. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nat Biotechnol 2003: 21: 513–518. 63 Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc Natl Acad Sci USA 2003: 100: 5413–5418. 64 Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, Chadburn A, Heissig B, Marks W, Witte L, Wu Y, Hicklin D, Zhu Z, Hackett NR, Crystal RG, Moore MA, Hajjar KA, Manova K, Benezra R, Rafii S. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001: 7: 1194–1201. 65 Malpe R, Baylink DJ, Linkhart TA, Wergedal JE, Mohan S. Insulin-like growth factor (IGF)-I, -II, IGF binding proteins (IGFBP)-3, -4, and -5 levels in the conditioned media of normal human bone cells are skeletal site-dependent. J Bone Miner Res 1997: 12: 423–430. 66 Mankani MH, Krebsbach PH, Satomura K, Kuznetsov SA, Hoyt R, Robey PG. Pedicled bone flap formation using transplanted bone marrow stromal cells. Arch Surg 2001: 136: 263–270. 67 Mayr-Wohlfart U, Waltenberger J, Hausser H, Kessler S, Gunther KP, Dehio C, Puhl W, Brenner RE. Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone 2002: 30: 472–477. 68 Midy V, Plouet J. Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts. Biochem Biophys Res Commun 1994: 199: 380–386. 69 Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG, Shi S. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 2003: 100: 5807–5812. 70 Miyazono K. TGF-beta signaling by Smad proteins. Cytokine Growth Factor Rev 2000: 11: 15–22. 71 Miyazono K, Maeda S, Imamura T. Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins. Oncogene 2004: 23: 4232–4237. 72 Mohler ER III, Rajagopalan S, Olin JW, Trachtenberg JD, Rasmussen H, Pak R, Crystal RG. Adenoviral-mediated gene transfer of vascular endothelial growth factor in critical limb ischemia: safety results from a phase I trial. Vasc Med 2003: 8: 9–13. 73 Murphy WL, Simmons CA, Kaigler D, Mooney DJ. Bone regeneration via a mineral substrate and induced angiogenesis. J Dent Res 2004: 83: 204–210. 74 Nakahara H, Bruder SP, Haynesworth SE, Holecek JJ, Baber MA, Goldberg VM, Caplan AI. Bone and cartilage formation in diffusion chambers by subcultured cells derived from the periosteum. Bone 1990: 11: 181–188. 75 Nakahara H, Bruder SP, Goldberg VM, Caplan AI. In vivo osteochondrogenic potential of cultured cells derived from the periosteum. Clin Orthop 1990: 223–232. 76 Nakashima M, Reddi AH. The application of bone morphogenetic proteins to dental tissue engineering. Nat Biotechnol 2003: 21: 1025–1032. 77 Needleman I, Tucker R, Giedrys-Leeper E, Worthington H. A systematic review of guided tissue regeneration for periodontal infrabony defects. J Periodontal Res 2002: 37: 380–388. 78 Nor JE, Peters MC, Christensen JB, Sutorik MM, Linn S, Khan MK, Addison CL, Mooney DJ, Polverini PJ. Engineering and characterization of functional human microvessels in immunodeficient mice. Lab Invest 2001: 81: 453–463. 79 Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol 2001: 2: Reviews 3005.1–3005.12. 80 Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. Receptor specificity of the fibroblast growth factor family. J Biol Chem 1996: 271: 15292–15297. 81 Partridge KA, Oreffo RO. Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies. Tissue Eng 2004: 10: 295–307. 82 Pelissier P, Villars F, Mathoulin-Pelissier S, Bareille R, Lafage-Proust MH, Vilamitjana-Amedee J. Influences of vascularization and osteogenic cells on heterotopic bone formation within a madreporic ceramic in rats. Plast Reconstr Surg 2003: 111: 1932–1941. 83 Peng H, Wright V, Usas A, Gearhart B, Shen HC, Cummins J, Huard J. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 2002: 110: 751–759. 84 Peters MC, Polverini PJ, Mooney DJ. Engineering vascular networks in porous polymer matrices. J Biomed Mater Res 2002: 60: 668–678. 85 Petite H, Viateau V, Bensaid W, Meunier A, De Pollak C, Bourguignon M, Oudina K, Sedel L, Guillemin G. Tissue-engineered bone regeneration. Nat Biotechnol 2000: 18: 959–963. 86 Pfeilschifter J, Mundy GR. Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones. Proc Natl Acad Sci USA 1987: 84: 2024–2028. 87 Pollok JM, Vacanti JP. Tissue engineering. Semin Pediatr Surg 1996: 5: 191–196. 88 Praemer A, Furner S, Rice DP, American Academy of Orthopaedic Surgeons. Musculoskeletal conditions in the United States, 1st edn. Park Ridge, IL: American Academy of Orthopaedic Surgeons, 1992. 89 Radke PW, Heinl-Green A, Frass OM, Griesenbach U, Ferrari S, Geddes DM, Alton EW. Effects of intramyocardial pVEGF(165) delivery on regional myocardial blood flow: evidence for a spatial 'delivery-efficacy' mismatch. Gene Ther 2004: 11: 1249–1255. 90 Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 2003: 9: 702–712. 91 Raiche AT, Puleo DA. In vitro effects of combined and sequential delivery of two bone growth factors. Biomaterials 2004: 25: 677–685. 92 Reddi AH. Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat Biotechnol 1998: 16: 247–252. 93 Rezania A, Healy KE. The effect of peptide surface density on mineralization of a matrix deposited by osteogenic cells. J Biomed Mater Res 2000: 52: 595–600. 94 Richardson TP, Peters MC, Ennett AB, Mooney DJ. Polymeric system for dual growth factor delivery. Nat Biotechnol 2001: 19: 1029–1034. 95 Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci 2001: 114: 853–865. 96 Rose FR, Oreffo RO. Bone tissue engineering: hope vs hype. Biochem Biophys Res Commun 2002: 292: 1–7. 97 Rowley JA, Madlambayan G, Mooney DJ. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999: 20: 45–53. 98 Ruhe PQ, Hedberg EL, Padron NT, Spauwen PH, Jansen JA, Mikos AG. rhBMP-2 release from injectable poly(dl-lactic-co-glycolic acid)/calcium-phosphate cement composites. J Bone Joint Surg Am 2003: 85-A(Suppl. 3): 75–81. 99 Saadeh PB, Mehrara BJ, Steinbrech DS, Dudziak ME, Greenwald JA, Luchs JS, Spector JA, Ueno H, Gittes GK, Longaker MT. Transforming growth factor-beta1 modulates the expression of vascular endothelial growth factor by osteoblasts. Am J Physiol 1999: 277: C628–637. 100 Sakakibara Y, Tambara K, Sakaguchi G, Lu F, Yamamoto M, Nishimura K, Tabata Y, Komeda M. Toward surgical angiogenesis using slow-released basic fibroblast growth factor. Eur J Cardiothorac Surg 2003: 24: 105–111 (discussion 112). 101 Schliephake H, Knebel JW, Aufderheide M, Tauscher M. Use of cultivated osteoprogenitor cells to increase bone formation in segmental mandibular defects: an experimental pilot study in sheep. Int J Oral Maxillofac Surg 2001: 30: 531–537. 102 Schmidmaier G, Wildemann B, Ostapowicz D, Kandziora F, Stange R, Haas NP, Raschke M. Long-term effects of local growth factor (IGF-I and TGF-beta 1) treatment on fracture healing. A safety study for using growth factors. J Orthop Res 2004: 22: 514–519. 103 Shea LD, Smiley E, Bonadio J, Mooney DJ. DNA delivery from polymer matrices for tissue engineering. Nat Biotechnol 1999: 17: 551–554. 104 Shea LD, Wang D, Franceschi RT, Mooney DJ. Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds. Tissue Eng 2000: 6: 605–617. 105 Shen HC, Peng H, Usas A, Gearhart B, Cummins J, Fu FH, Huard J. Ex vivo gene therapy-induced endochondral bone formation: comparison of muscle-derived stem cells and different subpopulations of primary muscle-derived cells. Bone 2004: 34: 982–992. 106 Sheridan MH, Shea LD, Peters MC, Mooney DJ. Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery. J Control Release 2000: 64: 91–102. 107 Shin H, Jo S, Mikos AG. Biomimetic materials for tissue engineering. Biomaterials 2003: 24: 4353–4364. 108 Shin M, Yoshimoto H, Vacanti JP. In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Eng 2004: 10: 33–41. 109 Simmons CA, Alsberg E, Hsiong S, Kim WJ, Mooney DJ. Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells. Bone 2004: 35: 562–569. 110 Smith MK, Peters MC, Richardson TP, Garbern JC, Mooney DJ. Locally enhanced angiogenesis promotes transplanted cell survival. Tissue Eng 2004: 10: 63–71. 111 Solchaga LA, Goldberg VM, Caplan AI. Cartilage regeneration using principles of tissue engineering. Clin Orthop 2001: S161–170. 112 Street J, Bao M, DeGuzman L, Bunting S, Peale FV Jr, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, Van Bruggen N, Redmond HP, Carano RA, Filvaroff EH. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA 2002: 99: 9656–9661. 113 Suggs LJ, Mikos AG. Development of poly(propylene fumarate-co-ethylene glycol) as an injectable carrier for endothelial cells. Cell Transplant 1999: 8: 345–350. 114 Tabata Y, Miyao M, Ozeki M, Ikada Y. Controlled release of vascular endothelial growth factor by use of collagen hydrogels. J Biomater Sci Polym Ed 2000: 11: 915–930. 115 Tarkka T, Sipola A, Jamsa T, Soini Y, Yla-Herttuala S, Tuukkanen J, Hautala T. Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues. J Gene Med 2003: 5: 560–566. 116 Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H, Amano K, Kishimoto Y, Yoshimoto K, Akashi H, Shimada K, Iwasaka T, Imaizumi T. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002: 360: 427–435. 117 Thomson JA, Marshall VS. Primate embryonic stem cells. Curr Top Dev Biol 1998: 38: 133–165. 118 Tsuda H, Wada T, Ito Y, Uchida H, Dehari H, Nakamura K, Sasaki K, Kobune M, Yamashita T, Hamada H. Efficient BMP2 gene transfer and bone formation of mesenchymal stem cells by a fiber-mutant adenoviral vector. Mol Ther 2003: 7: 354–365. 119 Tsutsumi S, Shimazu A, Miyazaki K, Pan H, Koike C, Yoshida E, Takagishi K, Kato Y. Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF. Biochem Biophys Res Commun 2001: 288: 413–419. 120 Urist MR. Bone: formation by autoinduction. Science 1965: 150: 893–899. 121 Villars F, Guillotin B, Amedee T, Dutoya S, Bordenave L, Bareille R, Amedee J. Effect of HUVEC on human osteoprogenitor cell differentiation needs heterotypic gap junction communication. Am J Physiol Cell Physiol 2002: 282: C775–C785. 122 Wang DS, Yamazaki K, Nohtomi K, Shizume K, Ohsumi K, Shibuya M, Demura H, Sato K. Increase of vascular endothelial growth factor mRNA expression by 1,25-dihydroxyvitamin D3 in human osteoblast-like cells. J Bone Miner Res 1996: 11: 472–479. 123 Wang DS, Miura M, Demura H, Sato K. Anabolic effects of 1,25-dihydroxyvitamin D3 on osteoblasts are enhanced by vascular endothelial growth factor produced by osteoblasts and by growth factors produced by endothelial cells. Endocrinology 1997: 138: 2953–2962. 124 Wiesmann HP, Nazer N, Klatt C, Szuwart T, Meyer U. Bone tissue engineering by primary osteoblast-like cells in a monolayer system and 3-dimensional collagen gel. J Oral Maxillofac Surg 2003: 61: 1455–1462. 125 Wozney JM, Rosen V. Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop 1998: 346: 26–37. 126 Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA. Novel regulators of bone formation: molecular clones and activities. Science 1988: 242: 1528–1534. 127 Xu CY, Inai R, Kotaki M, Ramakrishna S. Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. Biomaterials 2004: 25: 877–886. 128 Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J. Vascular-specific growth factors and blood vessel formation. Nature 2000: 407: 242–248. 129 Zhang WJ, Park C, Arentson E, Choi K. Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions. Blood 2004: 105: 111–114. 130 Zhu Y, Gao C, Liu Y, Shen J. Endothelial cell functions in vitro cultured on poly(l-lactic acid) membranes modified with different methods. J Biomed Mater Res 2004: 69A: 436–443. Citing Literature Volume41, Issue1June 2006Pages 109-122 ReferencesRelatedInformation

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