Study of the antioedema activity of some seaweed and sponge extracts from the mediterranean coast in mice
1993; Wiley; Volume: 7; Issue: 2 Linguagem: Inglês
10.1002/ptr.2650070213
ISSN1099-1573
AutoresMiguel Payá, Marı́a Luisa Ferrándiz, María‐Jesús Sanz, Gloria Bustos, Rafael Blasco, José Luis Rı́os, María José Alcaraz,
Tópico(s)Echinoderm biology and ecology
ResumoAbstract Chloroform and methanol extracts of ten marine species, seven seaweeds and three sponges, have been studied for possible, antioedema activities. The extracts were administered either topically or orally on TPA‐induced mouse ear oedema and on carrageenan mouse paw oedema, respectively. The most interesting seaweed extracts were found to be from Corallina elongata, Galaxaura oblongata, Laurencia obtusa and Udotea petiolata , where both extracts of each species induced a large antioedema effect in both models employed. None of the sponges assayed demonstrated antiinflammatory effects on carrageenan mouse paw oedema, however, some extracts elicited an inhibition of the oedema developed by TPA.
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