Membrane fusion mediated by ricin and viscumin
1998; Elsevier BV; Volume: 1371; Issue: 1 Linguagem: Inglês
10.1016/s0005-2736(98)00024-8
ISSN1879-2642
AutoresPeter Pohl, Yura N Antonenko, Veronika Yu. Evtodienko, Elena E. Pohl, Sapar M. Saparov, И. И. Агапов, Alexander Tonevitsky,
Tópico(s)Plant Virus Research Studies
ResumoThe ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle–vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity. Herein, fusion is hypothesized to allow the RIPs to leak across endocytic vesicles to approve their access to cytoplasmic ribosomes.
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