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Synthesis and Antimicrobial Studies of Some Novel Bis-[1,3,4]thiadiazole and Bis-thiazole Pendant to Thieno[2,3-b]thiophene Moiety

2012; Multidisciplinary Digital Publishing Institute; Volume: 13; Issue: 3 Linguagem: Inglês

10.3390/ijms13033661

1661-6596

Nabila A. Kheder, Yahia N. Mabkhot,

Synthesis and Characterization of Heterocyclic Compounds

The synthetic utility of 3,3’-(3,4-dimethylthieno[2,3-b]thiophene-2,5-diyl)bis (3-oxopropanenitrile) (1) in the synthesis of some novel bis-[1,3,4-thiadiazole] 6a–g and bis-thiazole 10 and 13 derivatives with thieno[2,3-b]thiophene moiety is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed promising results.