Post-mortem diagnosis of chronic Chagas's disease: comparative evaluation of three serological tests on pericardial fluid
1978; Oxford University Press; Volume: 72; Issue: 3 Linguagem: Inglês
10.1016/0035-9203(78)90202-x
ISSN1878-3503
AutoresE. R. Lopes, E Chapadeiro, S. M. Batista, J.G. Saraiva da Cunha, Arthur Farias Rocha, Lineu José Miziara, João Ulisses Ribeiro, Renato J. Patto,
Tópico(s)Viral Infections and Immunology Research
ResumoIn an attempt to improve the post-mortem diagnosis of Chagas's disease, the authors performed haemagglutination tests (HAT), fluorescent Trypanosoma cruzi antibody tests (FAT), and complement fixation tests (CFT) on the pericardial fluid obtained at autopsy of 50 individuals with Chagas's heart disease, and 93 patients in whom this disease was not thought to be present. The results demonstrate that all three tests are efficient for the post-mortem diagnosis of Chagas's disease but suggest that their combined use would detect more cases than would one isolated reaction only.
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