Composition of antibodies against acidic and basic azoproteins
1961; Elsevier BV; Volume: 92; Issue: 2 Linguagem: Inglês
10.1016/0003-9861(61)90356-3
ISSN1096-0384
AutoresSidney Fleischer, Richard L. Hardin, Jack Horowitz, Morris Zimmerman, Edwin L. Gresham, James Turner, J. Paul Burnett, Z. Stary, Felix Haurowitz,
Tópico(s)Animal health and immunology
ResumoRabbits were injected with azoproteins prepared by coupling bovine γ-globulin with diazotized arsanilic acid, anthranilic acid, or p-aminophenyltrimethylammonium chloride. The antibodies to these three antigens were isolated, purified, and analyzed. Their amino acid composition did not differ significantly. They contained approximately 3% carbohydrate. Their serological specificity may be due to differences in the amino acid sequence or tertiary structure, rather than to different amino acid content.
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