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Infection and Preterm Birth

2005; Elsevier BV; Volume: 32; Issue: 3 Linguagem: Inglês

10.1016/j.ogc.2005.03.001

1558-0474

Laura L. Klein, Ronald S. Gibbs,

Reproductive tract infections research

As many as 50% of spontaneous preterm births are infection-associated. Intrauterine infection leads to a maternal and fetal inflammatory cascade, which produces uterine contractions and may also result in long-term adverse outcomes , such as cerebral palsy . This article addresses the prevalence, microbiology, and management of intrauterine infection in the setting of preterm labor with intact membranes. It also outlines antepartum treatment of infections for the purpose of preventing preterm birth.