Portal de Periódicos da CAPES

Skin reactions to a urea‐containing cream

1981; Wiley; Volume: 7; Issue: 4 Linguagem: Inglês

10.1111/j.1600-0536.1981.tb04040.x

1600-0536

Marie Cramers, Jens Thormann,

Drug-Induced Adverse Reactions

Patch tests with a cream (Calmuril®) containing 10% urea were performed on 79 patients with eczematous skin disease; seven (9.9%) had positive tests. Patch tests with the in‐gradients of the cream were negative. It is suggested, that the positive patch test reactions are toxic, due to hypertonicity and acidity of the cream.