Fast Analysis of Anabolic Steroids in Urine Samples by Electrospray Ionization Tandem Mass Spectrometry
1996; Taylor & Francis; Volume: 29; Issue: 8 Linguagem: Inglês
10.1080/00032719608001489
ISSN1532-236X
AutoresYoon‐Seok Chang, Jung-Suk Jang, Bong Chul Chung,
Tópico(s)Mass Spectrometry Techniques and Applications
ResumoAbstract Unauthorized steroids were administered to volunteers and the presence of anabolic steroids in urine samples were directly confirmed by electrospray ionization mass spectrometry without using the prerequisite steps of enzymatic hydrolysis and trimethyl-chlorosilane derivatization. Further structure determination has been conducted by collisionally induced dissociation in a triple quadrupole tandem mass spectrometer. Overall, the electrospray ionization and tandem mass spectrometry methods prove to be simple, fast and sensitive for the analysis of anabolic steroids in urine samples. Korea Research Institute of Chemical Technology, Taejon, Korea. Doping Control Center, KIST, Seoul, Korea. Key Words: Anabolic SteroidsElectrospray IonizationTandem Mass Spectrometry Notes Korea Research Institute of Chemical Technology, Taejon, Korea. Doping Control Center, KIST, Seoul, Korea.
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