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Pre-eclampsia/Eclampsia

2001; Elsevier BV; Volume: 38; Issue: 2 Linguagem: Inglês

10.1053/s0272-6386(13)90043-3

1523-6838

Agnes B. Fogo,

Pregnancy and preeclampsia studies

The AJKD Atlas of Renal Pathology presents a compilation of figures on a specific pathologic entity. You may download the figures to create your own personal, non-commercial library of images or to create slides for teaching purposes. The AJKD Atlas of Renal Pathology presents a compilation of figures on a specific pathologic entity. You may download the figures to create your own personal, non-commercial library of images or to create slides for teaching purposes. Fig 2The classic lesion of pre-eclampsia/eclampsia, endotheliosis, is illustrated in this glomerulus. There is also evident glomerular visceral epithelial cell swelling. Occasionally glomerular visceral epithelial cells may contain hyaline droplets. Segmental double contours are also apparent, due to the interposition of mesangial cell cytoplasm processes. Mesangial and glomerular endothelial foam cells are not present in this biopsy, but may be present as part of the endotheliosis lesion postpartum. The presence of foam cells thus correlates with the timing of the biopsy. (Jones' silver stain, ×400).View Large Image Figure ViewerDownload Hi-res image Download (PPT) Fig 3The electron microscopic appearance of pre-eclampsia/eclampsia illustrates the swelling of glomerular endothelial cells with vacuolization and lipid material. Not illustrated here, myelin figures and dense bodies and amorphous subendothelial deposits related to fibrin/fibrinogen-related breakdown products may also be found in the mesangium and subendothelium. Visceral epithelial cells show vacuoles and lipid droplets. There may also be increased lucency of the lamina rara interna and interposition, not illustrated in this capillary loop. (Transmission electron microscopy, ×12000).View Large Image Figure ViewerDownload Hi-res image Download (PPT)