An isocyanide-based three-component reaction: synthesis of fully substituted N-alkyl-2-triphenylphosphoranylidene glutarimides
2006; Elsevier BV; Volume: 47; Issue: 31 Linguagem: Inglês
10.1016/j.tetlet.2006.05.164
ISSN1873-3581
AutoresAhmad Shaabani, Ebrahim Soleimani, Hamid Reza Khavasi, Ralf-Dieter Hoffmann, Ute Ch. Rodewald, Rainer Pöttgen,
Tópico(s)Click Chemistry and Applications
ResumoA three-component condensation reaction between an isocyanide, an electron-deficient acetylenic ester and (ethoxycarbonylmethyl)triphenylphosphonium bromide efficiently provides fully substituted N-alkyl-2-triphenylphosphoranylidene glutarimides in a one-pot reaction without any activation or modification.
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