Evaluation of Melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
1996; Elsevier BV; Volume: 58; Issue: 20 Linguagem: Inglês
10.1016/0024-3205(96)00160-9
ISSN1879-0631
AutoresRobert T. Dorr, Ruskin Lines, Norman Levine, Christine Brooks, Li Xiang, Victor J. Hruby, Mac E. Hadley,
Tópico(s)Dermatology and Skin Diseases
ResumoA pilot phase I study was conducted with a cyclic heptapeptide analog of α-melanocyte stimulating hormone (α-MSH). The lactam-bridged molecule, called Melanotan-II (MT-II), has the structure
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