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The role of the Y chromosome in human evolutionary studies

1996; Wiley; Volume: 5; Issue: 4 Linguagem: Inglês

10.1002/(sici)1520-6505(1996)5

1520-6505

Michael F. Hammer, Stephen L. Zegura,

Genetic diversity and population structure

Evolutionary Anthropology: Issues, News, and ReviewsVolume 5, Issue 4 p. 116-134 Article The role of the Y chromosome in human evolutionary studies† Michael F. Hammer, Michael F. HammerSearch for more papers by this authorStephen L. Zegura, Stephen L. ZeguraSearch for more papers by this author Michael F. Hammer, Michael F. HammerSearch for more papers by this authorStephen L. Zegura, Stephen L. ZeguraSearch for more papers by this author First published: 1996 https://doi.org/10.1002/(SICI)1520-6505(1996)5:4 3.0.CO;2-ECitations: 64 † The primary goal of Michael Hammer's research is a better understanding of the genetic and evolutionary factors that have influenced the distribution of human Y chromosomes over the last 250,000 years. Stephen Zegura's primary research interests include the early peopling of the Americas, the human biology of modern Native American populations, and the population structure of the eastern Adriatic. The two authors have recently collaborated on a worldwide synthesis of Y chromosome haplotype data, as well as with Dr. Tatiana Karafet from Novosibirsk, Siberia on a paternally based analysis of Native American origins. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Analyses of molecular genetic data have added a new dimension to human evolutionary research. Pioneering studies of variation in human populations were based on analyses of blood groups1 and electromorphs,2 both of which represent qualitative multistate phenotypes. With the development of recombinant DNA methods in the 1970s and 1980s, the focus shifted from gene products to a new and plentiful source of human variability, restriction fragment length polymorphisms (RFLPs).3,4 Finally, the addition of DNA sequencining survey data to the rapidly growing RFLP data base made it feasible for the first time to determine the exact number of nucleotide substitutions between different alleles, as well as to construct gene trees and reconstruct the phylogenetic history of populations.5–7 Citing Literature Volume5, Issue41996Pages 116-134 RelatedInformation