Enzymatic synthesis of β-D-glucuronides with in situ regeneration of uridine 5′-diphosphoglucuronic acid
1991; Elsevier BV; Volume: 47; Issue: 28 Linguagem: Inglês
10.1016/s0040-4020(01)87124-6
ISSN1464-5416
AutoresDaniel Gygax, Peter Spies, Tammo Winkler, Ulrike Pfaar,
Tópico(s)Glycogen Storage Diseases and Myoclonus
Resumoβ-D-glucuronides of 1 and 2 have been synthesized by a multi-enzyme system with in situ regeneration of uridine 5′-diphosphoglucuronic acid. Crude liver homogenate containing all enzymes involved in the multi-enzyme system was used for this stereoselective one-pot reaction.
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