Revisão Revisado por pares

The Role of Thymic Epithelium in the Establishment of Transplantation Tolerance

1993; Wiley; Volume: 133; Issue: 1 Linguagem: Inglês

10.1111/j.1600-065x.1993.tb01518.x

ISSN

1600-065X

Autores

António Coutinho, Josselyne Salaün, C. Corbel, António Bandeira, Nicole Le Douarin,

Tópico(s)

Diabetes and associated disorders

Resumo

Immunological ReviewsVolume 133, Issue 1 p. 225-240 The Role of Thymic Epithelium in the Establishment of Transplantation Tolerance Antonio Coutinho, Antonio Coutinho *Unite d'Immunobiologie, CNRS URA 359, Institut Pasteur, Paris.Search for more papers by this authorJosselyne Salaün, Josselyne Salaün +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorCatherine Corbel, Catherine Corbel +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorAntonio Bandeira, Antonio Bandeira +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorNicole Le Douarin, Nicole Le Douarin +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this author Antonio Coutinho, Antonio Coutinho *Unite d'Immunobiologie, CNRS URA 359, Institut Pasteur, Paris.Search for more papers by this authorJosselyne Salaün, Josselyne Salaün +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorCatherine Corbel, Catherine Corbel +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorAntonio Bandeira, Antonio Bandeira +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this authorNicole Le Douarin, Nicole Le Douarin +Institut d'Embryologie du CNRS et du College de France, Nogent-sur-Mame, France.Search for more papers by this author First published: June 1993 https://doi.org/10.1111/j.1600-065X.1993.tb01518.xCitations: 47AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Adams, T, Alpert, S. & Hanahan, D. (1987) Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells. Nature 325, 223. Agus, D, Surh, C. & Sprent, J. (1991) Reentry of T cells to the adult thymus is restricted to activated T cells. J. Exp. Med, 173, 1039. Bandeira, A., Coutinho, A., Burlen-Defranoux, O., Khazaal, I., Coltey, H., Jacquemart, F., Le Douarin, N. & Salaün. J. (1992) Thymic epithelium induces neither clonal deletion, nor anergy to Mls-la antigens. Eur J. Immunol., 11, 1397. Bandeira, A., Coutinho, A., Carnaud, C, Jacquemart, F. & Forni, L. (1989) Transplantation tolerance correlates with high levels of T- and B-lymphocyte activity. Proc. Natl. Acad. Sci. USA 86, 272. Belo, M., Corbel, C, Martin, C. & Le Douarin, N. M. (1989) Thymic epithelium toledzes chickens to embryonic grafts of quail bursa of Fabricius. Int. Immunol. 1, 105. Ben-Nun, A., Werkerle, H. & Cohen, I. R. (1981) Vaccination against autoimmune encephalomyelitis with T lymphocyte line cells reactive against myelin basic protein. Nature 292, 60. Billingham, R. E., Brent, L. & Medawar, P. B. (1953) Actively acquired tolerance of foreign cells. Nature 172, 603. Billingham, R. & Sivers, W. (1960) Studies on tolerance of the Y chromosome antigen in mice. J. Immunol., 85, 14. Bohme, J., Haskins, K., Stecha, P., Van Ewijk, W, LeMeur, M., Gerlinger, P., Benoist, C. & Mathis, D. (1989) Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant. Science 244, 1179. Cohen, I. R. (1986) Regulation of autoimmune disease: physiological and therapeutic. Immunol. Rev, 94, 5. Corbel, C, Belo, M., Martin, C. & LeDouarin, N. (1987) A novel method to bursectomize avian embryos and obtain quail chick bursal chimeras, IL Immune response of bursectomized chicks and chimeras and post-natal rejection of the grafted quail bursas. J. Immunol., 138, 2813. Corbel, C, Martin, C, Ohki, H., Coltey, M., Hlozanek, I. & LeDouarin, N. (1990) Evidence for peripheral mechanisms inducing tissue tolerance during ontogeny. Int. Immunol., 2, 33. Coutinho, A. (1989) Beyond clonal selection and network. Immunol. Rev, 110, 63. Coutinho, A. & Bandeira, A. (1989) Tolerize one, tolerize them all: on assertion versus ignorance of self as the basis for tolerance. Immunol. Today 10, 264. Coutinho, A., Coutinho, G., Grandien, A., Marcos, M. A. R. & Bandeira, A. (1992) Some reasons why deletion and anergy do not satisfactorily account for natural tolerance. Res. Immunol. 345, 143. Dorsch, S. & Roser, B. (1974) The clonal nature of alloantigen sensitive small lymphocytes in the recirculating pool of normal rats. Aust. J. Exp. Biot. Med. Sci, 52, 45. Dorsch, S. & Roser, B. (1975) T cells mediate transplantation tolerance. Nature 258, 174. Gaur, A., Haspel, R. Mayer, J. R & Garrison Fathman, C. (1993) Requirement for CD8+ cells in T cell receptor peptide-induced clonal unresponsiveness. Science 259, 91. Hämmerling, G., Schönrich, G., Momburg, E., Auphan, N., Malissen, M., Malissen, B., Schmitt-Verhulst, A.-M. & Arnold, B. (1991) Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen. Immunol. Rev. 122, 47. Heath, W., Allison, J., Hoffmann, M., Schönrich, G., Hämmerling, G., Arnold, B. & Miller, J. E. A. P. (1993) Autoimmune diabetes as a consequence of locally produced interteukin Nature (in press). Herold, K., Montag, A. & Buckingham, E. (1992) Induction of tolerance to autoimmune diabetes with islet antigens. J. Exp. Med, 176, 1107. Hünig, T. & Bevan, M. (1982) Antigen recognition by cloned cytotoxic T lymphocytes follows rules predicted by the altered-self hypothesis. J. Exp. Med, 155, 111. Khazaal, I., Salaün, J., Coltey, M., Caiman, E & Le Douarin, N. M. (1989) Restoration of T cell function in nude mice by grafting the epitheliomesenchymal thymic rudiment from 10 days old euthymic embryos. Cell Differ Dev, 26, 211. Lafferty, K., Prowse, S. & Simeonovic, C. (1983) Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Ann. Rev. Immunol. 1, 143. Lafferty, K. &. Woolnpugh, J. (1977) The origin and mechanism of allograft rejection. Immunol. Rev. 35, 231. LeDouarin, N., Corbel, C, Martin, C, Coltey, M. & Salaün, J. (1989) Induction of tolerance by embryonic thymic epithelial grafts in birds and mammals. Cold Spring Harbor Symp. Quant. Biot, 54, 777. Lo, D., Burkly, A. L., Flavell, R. A., Palmiter, R. D. & Brinster, R. L. (1989) Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. J. Exp. Med, 170, 87. Lo, D., Burkly, L. C., Widera, G., Cowing, C, Flavell, R. A., Palmiter, R. D. & Brinster, R. L. (1988) Diabetes and tolerance in transgenic mice expressing Class H MHC molecule in pancreatic beta ceils. Cell 53, 159. Lo, D., Freedman, J., Hesse, S., Palmiter, R. Brinster, R. & Sherman, L. (1992) Peripheral tolerance to an islet cell specific hem agglutinin transgene affects both CD4+ and CD8+ T cells. Eur. J. Immunol., 4, 1013. Lubaroff, D. M. & Silvers, W. K. (1973) The importance of chimerism in maintaining tolerance of skin allografts in mice. J. Immunol., 111, 65. MacDonald, H. R., Pedrazzini, T, Schneider, R. Louis, J. A., Zinkernagel, R. M. & Hengartner, H. (1988) Intrathymic elimination of M1sa-reactive (Vb6 +) cells during neonatal tolerance induction to MlsB-encoded antigens. J. Exp. Med, 167, 2005. Martin, C, Ohki-Hamazaki, H., Corbel, C, Coltey, M. & LeDouarin, N. (1991) Successful xenogeneic transplantation in embryos: induction of tolerance by extrathymically chick tissue grafted into quail. Develop. Immunol. 1, 265. Medawar, P. & Woodruff, M. (1958) The induction of tolerance by skin homografts on newborn rats. Immunology. 1, 27. Miller, J., Daitch, L., Rath, S. & Selsing, E. (1990) Tissue-specific expression of allogeneic class II MHC molecules induces neither tissue rejection nor clonal inactivation of alloreactive T cells. J. Immunol., 144, 334. Miller, J. E A. P, Morahan, G., Allison, J., Bhathal, P & Cox, K. (1989) T cell tolerance in transgenic mice expressing major histocompatibility class I molecules in defined tissues. Imm. Rev. 107, 109. Mohler, K., M. & Streilein, J. W. (1987) Tolerance to class II major histocompatibility complex molecules is maintained in the presence of endogenous interleukin 2-producing, toierogen-specific T lymphocytes. J. Immunol. 139, 2211. G. Möller, (Ed) (1991) Transgenic mice and immunological tolerance. Immunol. Rev. 122. Morahan, G., Allison, J. & Miller, J. E A. P. (1989) Tolerance of class I histocompatibility antigens expressed extrathymically. Nature 339, 622. Morahan, G., Brennan, E, Bhathal, R, Allison, J., Cox, K. & Miller, J. E A. R (1989) Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothioneine promoter. Proc. Natl. Acad. Sci. (USA) 86, 3782. Mueller, D. L., Jenkins, M. K. & Schwartz, R. H. (1989) Clonal expansion versus functional clona elimination. Ann. Rev Immunol., 7, 445. Murphy, K., Weaver, C., Elish, M., Allen, P & Loh, D. (1989) Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal deletion mechanism. Proc. Natl. Acad. Sci. (USA) 86, 10034. Ohashi, P. S., Oehen, S., Buerki, K., Pircher, H., Ohashi, C. T., Odermatt, B., Malissen, B., Zinkernagel, R. M. & Hentgarter, H. (1991) Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65, 305. Ohki, H., Martin, C, Coltey, M. & Le Douarin, N. M. (1988) Implants of quail thymic epithelium generate permanent tolerance in embryonic ally constructed quail/chick chimeras. Development 104, 619. Ohki, H., Martin, C, Corbel, C. Coltey, M. & Le Douarin, N. M. (1987) Tolerance induced by thymic epithelial grafts in birds. Science 237, 1032. Opelz, G, Sengar, D, Mickey, M. & Terasaki, P. (1973) Effect of blood transfusions on subsequent kidney transplants. Transplant. Proc, 5, 253. Pereira, P., Bandeira, A., Coutinho, A., Marcos, M. A. R., Toribio, M. L. & Martinez-A, C. (1989) V-region connectivity in T cell repertoires. Ann. Rev. Immunol., 7, 209. Posselt, A., Barker, C, Tomaszewski, J., Marksman, J., Choti, M. & Naji, A. (1990) Induction of donor-specific unresponsiveness by intrathymic islet transplantation. Science. 249, 1293. Powell, T & Streilein, J. W. (1990) Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells. J. Immunol. 144, 854. Roman, L., Simons, L., Hammer, R. Sambrook, J. & Gething, M.-J. (1990) The expression of influenza virus hem agglutinin in the pancreatic b cells of transgenic mice results in autoimmune diabetes. Cell 61, 383. Sakaguchi, S. & Sakaguchi, N. (1990) Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease. J. Exp. Med, 172, 537. Sakaguchi, S., Takahashi, T. & Nishizuka, Y. (1982) Study on the cellular events in postthymectomy autoimmune ionophoretic. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J. Exp. Med. 156, 1577. Salaün, J., Bandeira, A., Khazaal, I., Burlen-Defranoux, O., Thomas-Vaslin, V, Cottey, M., Le Douarin, N. & Coutinho, A. (1992) Transplantation tolerance is unrelated to super antigen-dependent deletion and anergy. Proc. Natl. Acad. Sci. USA 89, 10420. Salaün, J., Bandeira, A., Khazaal, L. Caiman, E. Coltey M., Coutinho, A. & Le Douarin, N. (1990) Thymic epitheliums tolerizes for histocompatibility antigens. Science 247, 1471. Sarvetnick, N., Liggitt, D., Pitts, S. L., Hansen, S. E. & Stewart, T A. (1988) Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52, 773. Sarvetnick, N., Shizuru, J., Liggitt, D., Martin, L., McIntyre, B., Gregory, A., Parslow, T. & Stewart, T (1990) Loss of pancreatic islet tolerance induced by b-cell expression of interferon-g. Nature 346, 844. Schönrich, G., Kalinke, U., Momburg, E, Malissen, M., Schmitt-Verhulst, A.-M., Malissen, B., Hammerling, G. & Arnold, B. (1991) Downregulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymically tolerance induction. Cell 65, 293. Starzl, T. E., Demetris, A. J., Murase, N., Thomson, A. W., Trucco, M. & Ricordi, C. (1993) Cell chimerism permitted by immunosuppressive drugs is the basis of organ transplant acceptance and tolerance. Immunol. Today (in press). Surh, C, Sprent, J. & Webb, S. (1993) Exclusion of circulating T cells from the thymus does not apply in the neonatal period. J. Exp, Med. 177, 379. Takei, I., Asaba, Y., Kasatani, T, Maruyama, T, Watanabe, K., Yanagawa, T. Saruta, T. & Ishii, T (1992) Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection. J. Autoimm. 5, 665. Waldmann, H., Cobbold, S. P., Qin, S., Benjamin, R. J. & Wise, M. (1989) Tolerance induction in the adult using monoclonal antibodies to CD4, CD8 and CDlla (LEA-1). Cold Spring Harbor Sympt, Quant, Biot. 54, 885. Webb, S. R. & Sprent, J. (1990) Induction of neonatal tolerance to Mls a antigens by CD8-I- T cells. Science 248, 1643. Citing Literature Volume133, Issue1June 1993Pages 225-240 ReferencesRelatedInformation

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