Revisão Revisado por pares

A REVIEW OF THE NEUROPHYSIOLOGICAL EFFECTS OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND OTHER PSYCHOTOMIMETIC AGENTS

1957; Wiley; Volume: 66; Issue: 3 Linguagem: Inglês

10.1111/j.1749-6632.1957.tb40744.x

ISSN

1749-6632

Autores

Edward V. Evarts,

Tópico(s)

Neurotransmitter Receptor Influence on Behavior

Resumo

Annals of the New York Academy of SciencesVolume 66, Issue 3 p. 479-495 A REVIEW OF THE NEUROPHYSIOLOGICAL EFFECTS OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND OTHER PSYCHOTOMIMETIC AGENTS Edward V. Evarts, Edward V. Evarts National Institute of Mental Health, National Institutes of Health, Public Health Science, Department of Health, Education, and Welfare, Bethesda, Md.Search for more papers by this author Edward V. Evarts, Edward V. Evarts National Institute of Mental Health, National Institutes of Health, Public Health Science, Department of Health, Education, and Welfare, Bethesda, Md.Search for more papers by this author First published: March 1957 https://doi.org/10.1111/j.1749-6632.1957.tb40744.xCitations: 46AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Adams, R. 1941-1942. Marihuana. Harvey Lectures. : 168– 197. 2 Bromberg, W. 1939. The effects of marihuana. In The Inter-Relationship of Mind and Body Research Publs. Assoc. Research Nervous Mental Diseases. 19: 180– 189. Williams & Wilkins. Baltimore , Md. 3 Kraepelin, E. 1914. Lectures on Clinical Psychiatry. William Wood & Co. New York , N. Y. . 4 Henderson, D. K. & R. D. Gillespie 1950. A Textbook of Psychiatry. Oxford Univ. Press. London , England & New York , N. Y. 5 Goodman, L. S & A. Gilman 1955. The Pharmacological Basis of Therapeutics. Macmillan. New York , N. Y. . 6 Hoch, P. H., H. H. Pennes & J. P. Cattell 1953. Psychoses produced by the administration of drugs. In Metabolic and Toxic Diseases of the Nervous System. Research Publs. Assoc. Research Nervous Mental Diseases. 32. Nilliams & Wilkins. Baltimore , Md. 7 McLaughlin, J. T., R. N. Zabarenko, P. B. Diana & B. Quinn 1953. Emotional reactions of rheumatoid arthritics to ACTH. Psychosomat. Med. 15: 187– 99. 8 Hoefer, P. F. A. & G. H. Glaser 1950. Effects of pituitary adrenocorticotropic hormone (ACTH) therapy: electroencephalographic and neuropsychiatric changes in fifteen patients. J. Am. Med. Assoc. 143: 620– 24. 9 Rome, H. P. & F. J. Braceland 1952. The psychological response to ACTH, cortisone, hydrocortisone, and related steroid substances. Am. J. Psychiat. 108: 641– 51. 10 Fox, H. M. & S. Gifford 1953. Psychological responses to ACTH and cortisone. Psychosomat. Med. 16: 614– 631. 11 Goolker, P. & J. Schein 1953. Psychic effects of ACTH and cortisone. Psychosomat. Med. 16: 589– 613. 12 Polatin, P., S. Lesse & M. M. Harris 1955. Use of large doses of cortisone in schizophrenia. Arch. Neurol. Psychiat. 73: 485– 95. 13 Pleasure, H. 1954. Psychiatric and neurological side-effects of isoniazid and iproniazid. Arch. Neurol. Psychiat. 72: 313– 320. 14 Crane, G. E. 1956. The psychiatric side-effects of iproniazid. Am. J. Psychiat. 112: 494– 501. 15 Stoll, W. A. 1947. Lysergsäure-diäthylamid, ein Phantasticum aus der Mutterkorn-gruppe. Schweiz. Arch. Neurol. Psychiat. 60: 279. 16 Beringer, K. 1927. Der Meskalinrausch. Julius Springer. Berlin , Germany . 17 Hoffer, A., H. Osmond & J. Smythies 1954. Schizophrenia: a new approach II. Result of a year's research. J. Mental Sci. 100: 29– 45. 18 Iberico, C. C. 1941. Ayahuasca. Bol. Mus. Hist. Nat. Lima, Peru. 5: 313. 19 Rowntree, D. W., S. Nevin & A. Wilson 1950. The effects of DFP in schizophrenia and manic depressive psychosis. J. Neurol. Neurosurg. Psychiat. 13: 47– 59. 20 Grob, D., A. M. Harvey, O. Langworthy & J. O. Lillienthal, Jr. 1947. The administration of DFP to man. III. Effect on the central nervous system with special reference to the electrical activity of the brain. Bull. Johns Hopkins Hosp. 81: 257– 266. 21 Grob, D. & A. M. Harvey 1949. Observations on the effects of tetraethyl pyrophosphate (TEPP) in man, and on its use in the treatment of myasthenia gravis. Bull. Johns Hopkins Hosp. 84: 532– 567. 22 Lasagna, L. & H. K. Beecher 1954. The analgesic effectiveness of nalorphine and nalorphine-morphine combinations in man. J. Pharm. Exptl. Therap. 112: 356– 363. 23 Wikler, A. 1954. Clinical and electroencephalographic studies on the effects of mescaline, N-allylnormorphine and morphine in man. J. Nervous Mental Disease. 120: 157– 175. 24 Woolley, D. W. & E. Shaw 1954. A biochemical and pharmacological suggestion about certain mental disorders. Proc. Natl. Acad. Sci. U. S. 40: 228– 231. 25 Cachera, M. R. 1942. Le traitement du syndrome de Raynaud par l'yohimbine. Bull. mém. soc. méd. hôp. Paris. 58: 345– 47. 26 Meyer, W. B. 1924. Yohimbin poisoning. J. Am. Med. Assoc. 83: 1929. 27 Schiller, M. Q. 1936. Yohimbine treatment of dementia praecox. Elgin Papers. 2: 246– 49. 28 Beccle, H. C. & B. S. Lond 1935. On the action of certain drugs in schizophrenia. J. Mental Sci. 81: 46– 60. 29 Fabing, H. D. & J. R. Hawkins Intravenous bufotenine injection in the human. Science. To be published. 30 Isbell, H. Personal communication. 31 Nachmansohn, D. 1946. Chemical mechanism of nerve activity. Ann. N. Y. Acad. Sci. 47(4): 395– 428. 32 Koelle, G. B. & A. Gilman 1949. Anticholinesterase drugs. Pharmacol. Revs. 1: 166– 216. 33 Feldberg, W. 1950. The role of acetylcholine in the central nervous system. Brit. Med. Bull. 6: 312– 321. 34 Marrazzi, A. S. & E. R. Hart 1955. Relationship of hallucinogens to adrenergic cerebral neurohumors. Science. 121: 365– 367. 35 Marrazzi, A. S. & E. R. Hart 1955. Evoked cortical responses under the influence of hallucinogens and related drugs. Electroencephalog. and Clin. Neurophysiol. 7: 146. 36 Purpura, D. P. Electrophysiological analysis of psychotogenic drug action. Trans. Am. Neurol. Assoc. To be published. 37 Purpura, D. P. 1956. Electrophysiological analysis of psychotogenic drug action. Arch. Neurol. Psychiat. 75: 122– 131, 132–143. 38 Rovetta, P. 1956. Effect of mescaline and L.S.D. on evoked responses especially of the optic system of the cat. Electroencephalog. and Clin. Neurophysiol. 8: 15– 24. 39 Evarts, E. V., W. Landau, W. H. Freygang, Jr. & W. H. Marshall 1955. Some effects of lysergic acid diethylamide and bufotenine on electrical activity in the cat's visual system. Am. J. Physiol. 182: 594– 598. 40 Evarts, E. V. & A. Schulman Unpublished observations. 41 Evarts, E. V. 1956. Some effects of bufotenine and lysergic acid diethylamide on the monkey. Arch. Neurol. Psychiat. 76: 49– 53. 42 Evarts, E. V. & W. H. Marshall Effects of LSD on excitability of the lateral geniculate. Trans. Am. Neurol. Assoc. To be published. 43 Evarts, E. V. & J. R. Hughes Effects of physiological subnormality and LSD on post-tetanic potentiation of lateral geniculate potentials. Am. J. Physiol. 183: 614. 44 Hutter, O. F. 1952. Post-tetanic restoration of neuromuscular transmission blocked by d-tubocurarine. J. Physiol. 118: 216– 227. 45 Boyd, T. E. 1932. Recovery of the tongue from curare paralysis, following prolonged stimulation of the hypoglossal nerve. Am. J. Physiol. 100: 569– 575. 46 Killam, K. F. & E. K. Killam 1956. The action of lysergic acid diethylamide on central afferent and limbic pathways in the cat,. J. Pharmacol. Exptl. Therap. 116: 35– 36. 47 Slater, I. H., K. H. Davis, D. E. Leary & E. S. Boyd 1955. The action of serotonin and lysergic acid diethylamide on spinal reflexes. J. Pharmacol. Exptl. Therap. 113: 48– 49. 48 Hart, E. R., T. W. Langfitt & A. S. Marrazzi 1956. Some cerebral synaptic aspects of the pharmacology of toxic psychoses, tranquilizers, and antidotes. J. Pharmacol. Exptl. Therap. 116: 27– 28. 49 Hart, E. R. & A. S. Marrazzi 1952. Cerebral synaptic action of mescaline. J. Pharmacol. Exptl. Therap. 106: 349. 50 Marrazzi, A. S. & E. R. Hart 1953. Comparison of the effect on evoked cortical synaptic response of mescaline, amphetamine, and adrenaline. Electroencephalog, and Clin. Neurophysiol. 5: 317– 318. 51 Pennes, H. H. The effects of mescaline on evoked cortical optic responses in the anesthetized cat. In LSD and Mescaline in Experimental Psychiatry. Grune & Stratton. New York , N. Y. To be published. 52 Delay, J. 1953. Étude de l'action du L.S.D. 25 sur le lapin. Electroencephalog. and Clin. Neurophysiol. 5: 130– 131. 53 Delay, J., F. Lhermitte & G. & J. Verdeaux 1952. Modifications de l'Clectrocorti-cogramme du lapin par la diéthylamide de l'acide d-lysergique (LSD-25). Rev. neurol. 86: 81– 88. 54 Bradley, P. B. 1953. The effects of some drugs on the electrical activity of the brain in the cat. Electroencephalog, and Clin. Neurophysiol. 5: 471. 55 Bradley, P. B. & J. Elkes 1953. The effect of amphetamine and D-lysergic acid diethylamide (LSD 25) on the electrical activity of the brain of the conscious cat. J. Physiol. 120: 13P– 14P. 56 Schwarz, B. E., K. G. Wakim, R. G. Bickford & F. R. Lichtenheld 1956. Behavioral and electroencephalographic effects of hallucinogenic drugs. Arch. Neurol. Psychiat. 75: 83– 90. 57 Rinaldi, F. & H. E. Himwich 1955. Drugs affecting psychotic behavior and the function of the mesodiencephalic activating system. Diseases of Nervous System. 16: 133– 141. 58 Himwich, H. E. The cerebral electrographic changes induced by LSD and mescaline are corrected by Frenquel. J. Nervous Mental Disease. To be published. 59 Rinaldi, F. & H. E. Himwich 1955. Frenquel corrects certain cerebral electrographic changes. Science. 122: 198– 199. 60 Rinkel, M., H. J. DeShon, R. W. Hyde & H. C. Solomon 1952. Experimental schizophrenia-like symptoms. Am. J. Psychiat. 108: 572– 578. 61 Gastaut, H., S. Ferrer & C. Castells 1953. Action de la diéthylamide de l'acide d-lysergique (LSD 25) sur les fonctions psychiques et 1'électroencéphalogramme. Confinia Neurol. 13: 102– 120. 62 Forrer, G. R. & R. D. Goldner 1951. Experimental physiological studies with lysergic acid diethylamide (LSD–25). Arch. Neurol. Psychiat. 65: 581– 588. 63 Elkes, J., C. Elkes & P. B. Bradley 1954. The effect of some drugs on the electrical activity of the brain, and on behaviour. J. Mental Sci. 100: 125– 128. 64 Bradley, P. B., C. Elkes & J. Elkes 1953. On some effects of lysergic acid diethylamide (L.S.D. 25) in normal volunteers. J. Physiol. 121: 50P. 65 Chweitzer, A., E. Geblewicz & W. Liberson 1937. Action de la mescaline sur les ondes alpha (rhythme de Berger) chez l'homme. Compt. rend. Soc. biol. 124: 1296– 99. 66 Chweitzer, A., E. Geblewicz & W. Liberson 1936. etude de 1'électroencépha-logramme humain dans un cas d'intoxication mescalinique. Ann. Psychol. 37: 94– 98. 67 Rubin, M. A., W. Malamud & J. M. Hope 1942. The electroencephalogram and psychopathological manifestations in schizophrenia as influenced by drugs. Psychosomat. Med. 4: 355– 361. 68 Wikler, A. 1952. Clinical and electroencephalographic studies on the effects of mescaline, N-allylnormorphine and morphine in man. Electroencephalog. and Clin. Neurophysiol. 4: 378– 79. 69 Denber, H. C. B. & S. Merlis 1955. Studies on mescaline I. Action in schizophrenic patients. Psychiat. Quart. 29: 421– 429. 70 Merlis, S. & W. Hunter 1955. Studies on mescaline II. Electroencephalogram in schizophrenics. Psychiat. Quart. 29: 430– 432. 71 Denber, H. C. B. 1955. Studies on mescaline. III. Action in epileptics. Psychiat. Quart. 29: 433– 438. 72 Wikler, A. 1952. Pharmacologic dissociation of behavior and EEG "sleep patterns" in dogs: morphine, N-allylnormorphine, and atropine. Proc. Soc. Exptl. Biol. Med. 79: 261– 265. 73 Wikler, A., H. F. Fraser & H. Isbell 1953. N-Allylnormorphine: effects of single doses and precipitation of acute "abstinence syndromes" during addiction to morphine, methadone or heroin in man (postaddicts). J. Pharmacol. Exptl. Therap. 109: 8– 20. 74 Szatmari, A., A. Hoffer & R. Schneider 1955. The effect of adrenochrome and niacin on the electroencephalogram of epileptics. Am. J. Psychiat. 111: 603– 616. 75 Williams, E. G., C. K. Himmelsbach, A. Wikler, D. C. Ruble & B. J. Lloyd, Jr. 1946. Studies on marihuana and pyrahexyl compound. U. S. Public Health Repts. 61: 1059– 1083. 76 Wikler, A. & B. J. Lloyd, Jr. 1945. Effect of smoking marihuana cigarettes on cortical electrical activity. Federation Proc. 4: 141– 142. 77 Welsh, J. H. 1954. Marine invertebrate preparations useful in the bioassay of acetyl-choline and 5-hydroxytryptamine. Nature. 173: 955– 956. 78 Welsh, J. H. 1954. Hydroxytryptamine: a neurohormone in the invertebrates. Federation Proc. 13: 162– 163. 79 Gaddum, J. H. 1953. Antagonism between lysergic acid diethylamide and S-hydroxytryptamine. J. Physiol. 121: 15P. 80 Gaddum, J. H. & K. A. Hameed 1954. Drugs which antagonize 5-hydroxytryptamine. Brit. J. Pharmacol. 9: 240– 248. 81 Ginzel, K. H. & S. R. Kottegoda 1953. A study of the vascular actions of 5-hydroxy-tryptamine, tryptamine, adrenaline, and noradrenaline. Quart. J. Exptl. Physiol. 38: 225– 231. 82 Woolley, D. W. & E. Shaw 1954. Some neurophysiological aspects of serotonin. Brit. Med. J. 2: 122– 126. 83 Shore, P. A., S. L. Silver & B. B. Brodie 1955. Interaction of serotonin and lysergic acid diethylamide (LSD) in the central nervous system. Experientia. 11: 272– 273. 84 Evarts, E. V. Effects of a series of indoles on synaptic transmission in the lateral geniculate nucleus of the cat. Proc. Third Symposium Neurochem 3. Paul B. Hoeber, Inc. New York , N. Y . To be published. 85 Cerletti, A. & E. Rothlin 1955. Role of 5-hydroxytryptamine in mental diseases and its antagonism to lysergic acid derivatives. Nature. 176: 785– 786. 86 Brown, B. B., R. Feldman & D. L. Braun 1955. Pharmacologic studies of an LSD antagonist 4-piperidyl diphenyl carbinol hydrochloride. Federation Proc. 14: 322. 87 Fabing, H. D. 1955. New blocking agent against the development of LSD–25 psychosis. Science. 121: 208– 210. 88 Isbell, H. Federation Proc. To be published. 89 Isbell, H. Federation Proc. To be published. 90 Bradley, P. B. & A. J. Hance 1955. The effect of chlorpromazine on the electrical activity of the brain of the conscious cat. J. Physiol. 129: 50P– 51P. 91 Hoch, P. H. 1955. Experimental psychiatry. Am. J. Psychiat. 111: 787– 790. 92 Akelaitis, A. J. 1944. Study of gnosis, praxis, and language following section of the corpus callosum and anterior commissure. J. Neurosurg. 1: 94– 102. 93 Sperry, R. W., N. Miner & R. E. Myers 1955. Visual pattern perception following subpial slicing and tantalum wire implantations in the visual cortex. J. Comp. and Physiol. Psychol. 48: 50– 58. 94 Marrazzi, A. S. 1950. Cholineraic excitation and adrenergic inhibition common to peripheral and central synapses. In The Biology of Mental Health and Disease. : 376– 384. Paul B. Hoeber, Inc. New York , N. Y. 95 Rinaldi, F. & H. E. Himwich 1955. A comparison of effects of reseraine and some barbiturates on the electrical activity of cortical and subcortical structures of the brain of rabbits. Ann. N. Y. Acad. Sci. 61(1): 27– 35. 96 Klüver, H. 1942. Mechanisms of hallucinations. In Studies in Personality. Q. McNeniar, Ed. : 175. McGrawHill. New York , N. Y. & London , England . 97 Bartlet, J. E. A. 1951. A case of organized visual hallucinations in an old man with cataract, and their relation to the phenomena of the phantom limb. Brain. 74: 363– 373. 98 Colman, W. S. 1894. Hallucinations in the sane, associated with local organic disease of the sensory organs. Brit. Med. J. 1: 1015– 17. 99 Lippman, C. W. 1952. Certain hallucinations peculiar to migraine. J. Nervous Mental Disease. 116: 346– 351. 100 Wagener, H. P. Visual hallucinations. 1948. Am. J. Med. Sci. 116: 226– 232. 101 Hebb, D. O. 1949. The Organization of Behavior; a Neuropsychological Theory. John Wiley & Sons, Inc. New York , N. Y. . Citing Literature Volume66, Issue3The Pharmacology of Psychotomimetic and Psychotherapeutic DrugsMarch 1957Pages 479-495 ReferencesRelatedInformation

Referência(s)