4-Carboxymethoxy-5,7-Dinitroindolinyl-Glu: An Improved Caged Glutamate for Expeditious Ultraviolet and Two-Photon Photolysis in Brain Slices
2007; Society for Neuroscience; Volume: 27; Issue: 25 Linguagem: Inglês
10.1523/jneurosci.1519-07.2007
ISSN1529-2401
AutoresGraham C. R. Ellis‐Davies, M Matsuzaki, Martin Paukert, Haruo Kasai, Dwight E. Bergles,
Tópico(s)Photoreceptor and optogenetics research
ResumoCaged neurotransmitters are useful photochemical tools for selective stimulation of synapses and other transmitter receptors. Before illumination, the caged compound is biologically inert. Photolysis breaks a covalent bond, liberating the caged neurotransmitter. Release can be rapid, so the
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