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Increased plasma histamine levels in migraine patients

1982; Wiley; Volume: 12; Issue: 2 Linguagem: Inglês

10.1111/j.1365-2222.1982.tb01633.x

1365-2222

R V Heatley, JA Denburg, Nadine Bayer, J. Bienenstock,

Circadian rhythm and melatonin

Summary Whole blood and plasma histamine levels, peripheral basophil and eosinophil counts and serum immunoglobulins have been measured in a group of eighteen patients with migraine in remission and in twelve of these patients during a headache attack. Plasma histamine levels were significantly elevated ( P < 0.0005) in patients with migraine both during headache attacks and symptom‐free periods.