Artigo Revisado por pares

Edrophonium: An aid in the diagnosis of acute organophosphate poisoning

1986; Wiley; Volume: 19; Issue: 5 Linguagem: Inglês

10.1002/ana.410190517

ISSN

1531-8249

Autores

Ricardo A. Maselli, John H. Jacobsen, Jean‐Paul Spire,

Tópico(s)

Muscle activation and electromyography studies

Resumo

Abstract Unsuspected accidental cutaneous exposure to an organophosphate insecticide caused flaccid paralysis in a 10‐year‐old girl. Electromyogram demonstrated repetitive compound muscle action potentials in response to a single stimulus of nerve; decremental response, more prominent at higher rates of stimulation; worsening of decremental response after edrophonium injection; and normal nerve conduction velocities. Electromyogram with repetitive nerve stimulation and an edrophonium test may provide a simple and rapid method for diagnosis of acute organophosphate poisoning.

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