Artigo Acesso aberto Revisado por pares

The biological half-life of radioactive phosphorus in the blood of patients with leukemia.I. Whole blood—with deviations of observations from predicted values and an estimate of total-phosphorus turnover rate

1950; Wiley; Volume: 3; Issue: 6 Linguagem: Inglês

10.1002/1097-0142(1950)3

ISSN

1097-0142

Autores

Harold Tivey, Edwin E. Osgood, Elizabeth Klink, Maude McKenzie, Margret E. Hughes, Joan Ort, Ivan Gustafson, M. F. Fuller, Victor Klobucher, Hugh Stoddard,

Tópico(s)

Nutrition and Health in Aging

Resumo

CancerVolume 3, Issue 6 p. 992-1002 ArticleFree Access The biological half-life of radioactive phosphorus in the blood of patients with leukemia. I. Whole blood—with deviations of observations from predicted values and an estimate of total-phosphorus turnover rate Harold Tivey B.A., Harold Tivey B.A. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorEdwin E. Osgood M.D., Edwin E. Osgood M.D. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorElizabeth Klink B.S., Elizabeth Klink B.S. Technical Assistance Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMaude McKenzie, Maude McKenzie Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMargret E. Hughes B.A., Margret E. Hughes B.A. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorJoan Ort B.S., Joan Ort B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorIvan Gustafson B.S., Ivan Gustafson B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMalcolm Fuller B.S., Malcolm Fuller B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorVictor Klobucher B.S., Victor Klobucher B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorHugh Stoddard B.S., Hugh Stoddard B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this author Harold Tivey B.A., Harold Tivey B.A. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorEdwin E. Osgood M.D., Edwin E. Osgood M.D. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorElizabeth Klink B.S., Elizabeth Klink B.S. Technical Assistance Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMaude McKenzie, Maude McKenzie Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMargret E. Hughes B.A., Margret E. Hughes B.A. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorJoan Ort B.S., Joan Ort B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorIvan Gustafson B.S., Ivan Gustafson B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorMalcolm Fuller B.S., Malcolm Fuller B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorVictor Klobucher B.S., Victor Klobucher B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this authorHugh Stoddard B.S., Hugh Stoddard B.S. Division of Experimental Medicine, Department of Medicine, University of Oregon Medical School, Portland, OregonSearch for more papers by this author First published: 1950 https://doi.org/10.1002/1097-0142(1950)3:6 3.0.CO;2-WCitations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Doan, C. A.; Wiseman, B. K.; Wright, C.-S.; Geyer, J. H.; Myers, W., and Myers, J. W.: Radioactive phosphorus, P32: a six-year clinical evaluation of internal radiation therapy. J. Lab. & Clin. Med. 32: 943–969, 1947. CASPubMedWeb of Science®Google Scholar 2 Erf, L. A.: Primary polycythemia; remissions induced by therapy with radiophosphorus. Blood 1: 202–208, 1946. PubMedWeb of Science®Google Scholar 3 Erf, L. A., and Lawrence, J. H.: Clinical studies with the aid of radioactive phosphorus. I. The absorption and distribution of radio-phosphorus in the blood and its excretion by normal individuals and patients with leukemia. I. Clin. Investigation 20: 567–575, 1941. 10.1172/JCI101249 CASPubMedWeb of Science®Google Scholar 4 Erf, L. A.; Tuttle, L. W., and Lawrence, J. H.: Clinical studies with the aid of radio-phosphorus. IV. The retention in blood, the excretion and the therapeutic effect of radio-phosphorus on patients with leukemia. Ann. Int. Med. 15: 487–543, 1941. 10.7326/0003-4819-15-3-487 CASGoogle Scholar 5 Fisher, R. A.: Statistical Methods for Research Workers, 3d ed. Edinburgh. Oliver and Boyd. 1930. Google Scholar 6 Kamen, M. D.: Radioactive Tracers in Biology; an Introduction to Tracer Methodology. New York. Academic Press. 1947. Google Scholar 7 Lawrence, J. H.; Dobson, R. L.; Low-Beer, B. V. A., and Brown, B. R.: Chronic myelogenous leukemia; a study of 129 cases in which treatment was with radioactive phosphorus. J.A.M.A. 136: 672–677, 1948. 10.1001/jama.1948.02890270014004 CASPubMedWeb of Science®Google Scholar 8 Low-Beer, B. V. A., and Treadwell, A. de G.: Clinical studies with the aid of radio-phosphorus. V. Early effects of small amounts of radio-phosphorus on blood cell levels, uptake, and excretion. J. Lab. & Clin. Med. 27: 1294–1305, 1942. CASWeb of Science®Google Scholar 9 Marinelli, L. D., and Goldschmidt, B.: The concentration of P32 in some superficial tissues of living patients. Radiology 39: 454–463, 1942. 10.1148/39.4.454 CASGoogle Scholar 10 Osgood, E. E.: Differential diagnosis and treatment of the leukemias. Northwest Med. 47: 181–185; 257–260, 1948. CASPubMedGoogle Scholar 11 Reinhard, E. H.; Moore, C. V.; Bierbaum, O. S., and Moore, S.: Radioactive phosphorus as a therapeutic agent; a review of the literature and analysis of the results of treatment of 155 patients with various blood dyscrasias, lymphomas, and other malignant neoplastic diseases. J. Lab. & Clin. Med. 31: 107–215, 1946. PubMedWeb of Science®Google Scholar 12 United States Atomic Energy Commission, Isotopes Division: Circular D-2. References on therapeutic and tracer uses of P32. Oak Ridge, Tennessee. November, 1947. Google Scholar 13 Warren, S.: The retention of radioactive phosphorus in leukemic patients. Cancer Research 3: 872–876, 1943. Google Scholar Citing Literature Volume3, Issue61950Pages 992-1002 ReferencesRelatedInformation

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