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Mapping of CNS sigma 1 receptors in the conscious monkey: Preliminary PET study with [ 11 C]SA4503

2001; Wiley; Volume: 40; Issue: 3 Linguagem: Inglês

10.1002/syn.1046

1098-2396

Kiichi Ishiwata, Hideo Tsukada, Kazunori Kawamura, Yuichi Kimura, Shingo Nishiyama, Tadayuki Kobayashi, Kiyoshi Matsuno, Michio Senda,

Nicotinic Acetylcholine Receptors Study

SynapseVolume 40, Issue 3 p. 235-237 Short Communication Mapping of CNS sigma1 receptors in the conscious monkey: Preliminary PET study with [11C]SA4503 Kiichi Ishiwata, Corresponding Author Kiichi Ishiwata [email protected] Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanPositron Medical Center, Tokyo Metropolitan Institute of Gerontology, 1-1 Naka-cho, Itabashi, Tokyo, 173-0022, JapanSearch for more papers by this authorHideo Tsukada, Hideo Tsukada Central Research Laboratory, Hamamatsu Photonics K.K., Hamakita, JapanSearch for more papers by this authorKazunori Kawamura, Kazunori Kawamura Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan Sumitomo Accelerator Service, Tokyo, JapanSearch for more papers by this authorYuichi Kimura, Yuichi Kimura Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this authorShingo Nishiyama, Shingo Nishiyama Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this authorTadayuki Kobayashi, Tadayuki Kobayashi Central Research Laboratories, Santen Pharmaceutical Co., Ltd., Osaka, JapanSearch for more papers by this authorKiyoshi Matsuno, Kiyoshi Matsuno Central Research Laboratories, Santen Pharmaceutical Co., Ltd., Osaka, JapanSearch for more papers by this authorMichio Senda, Michio Senda Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this author Kiichi Ishiwata, Corresponding Author Kiichi Ishiwata [email protected] Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanPositron Medical Center, Tokyo Metropolitan Institute of Gerontology, 1-1 Naka-cho, Itabashi, Tokyo, 173-0022, JapanSearch for more papers by this authorHideo Tsukada, Hideo Tsukada Central Research Laboratory, Hamamatsu Photonics K.K., Hamakita, JapanSearch for more papers by this authorKazunori Kawamura, Kazunori Kawamura Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan Sumitomo Accelerator Service, Tokyo, JapanSearch for more papers by this authorYuichi Kimura, Yuichi Kimura Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this authorShingo Nishiyama, Shingo Nishiyama Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this authorTadayuki Kobayashi, Tadayuki Kobayashi Central Research Laboratories, Santen Pharmaceutical Co., Ltd., Osaka, JapanSearch for more papers by this authorKiyoshi Matsuno, Kiyoshi Matsuno Central Research Laboratories, Santen Pharmaceutical Co., Ltd., Osaka, JapanSearch for more papers by this authorMichio Senda, Michio Senda Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanSearch for more papers by this author First published: 09 April 2001 https://doi.org/10.1002/syn.1046Citations: 32AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES Helmeste DM, Tang SW, Bunney WE Jr, Potkin SG, Jones EG. 1996. Decrease in σ but no increase in striatal dopamine D4 sites in schizophrenic brains. Eur J Pharmacol 314: R3–R4. Jansen KLR, Faull RLM, Storey P, Leslie RA. 1993. Loss of sigma binding sites in the CA1 area of the anterior hippocampus in Alzheimer's disease correlates with CA1 pyramidal cell loss. Brain Res 623: 299–302. Junien JL, Leonard BE. 1989. Drugs acting on sigma and phencyclidine receptors: a review of their nature, function and possible therapeutic importance. Clin Neuropharmcol 12: 353–374. Kawamura K, Ishiwata K, Tajima H, Ishii S, Matsuno K, Homma Y, Senda M. 2000a. In vivo evaluation of [11C]SA4503 as a PET ligand for mapping CNS sigma1 receptors. Nucl Med Biol 27: 255–261. Kawamura K, Ishiwata K, Shimada Y, Kimura Y, Kobayashi T, Matsuno K, Homma Y, Senda M. 2000b. 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Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biol Psychiatry 29: 41–54. Citing Literature Volume40, Issue31 June 2001Pages 235-237 ReferencesRelatedInformation