The hydration of protein secondary structures
1987; Wiley; Volume: 213; Issue: 2 Linguagem: Inglês
10.1016/0014-5793(87)81535-1
ISSN1873-3468
Autores Tópico(s)Mass Spectrometry Techniques and Applications
ResumoThe hydration of the main‐chain carbonyl (CO) groups in proteins have been studied using infra‐red spectroscopy, and computer‐graphics analysis of high resolution protein crystal structures. The IR measurements indicate that the strength of water binding to the CO groups is lower in β‐sheet proteins compared with α‐helical ones. Analysis of the protein crystal structures shows that this is due primarily to differences in the geometry ofwater‐CO group interactions in the two types of secondary structure.
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