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Treatment of Pediatric non‐Hodgkin lymphomas in a country with limited resources: Results of the first national protocol in Nicaragua

2006; Wiley; Volume: 50; Issue: 1 Linguagem: Inglês

10.1002/pbc.21046

1545-5017

F. Baez, Marta Pillon, Luca Manfredini, Emilio A. Ocampo, G Mendez, Roberta Ortiz, Rosario Palacios, Tamara González Gutiérrez, Gloria Tridello, Valentino Conter, MG Valsecchi, Franca Fossati Bellani, Franco Cavalli, Giuseppe Masera, A Rosolen,

Childhood Cancer Survivors' Quality of Life

We report the results of a protocol for the diagnosis and treatment of pediatric non-Hodgkin lymphomas (NHL) conducted in Nicaragua in the context of an international collaborative program. Fifty-three children with NHL treated between 1996 and 2003 were retrospectively evaluated. Therapy was designed based on local drug availability and affordability with dose and schedule adaptations for Burkitt and lymphoblastic lymphomas. With a median follow-up of 3 years, the projected 9-year overall survival was 63% and event-free survival 53%. The treatment was efficacious, feasible, and well tolerated in spite of the local socio-economical conditions.