Hyperpathic Disorder From Intrathecal Alumina Gel Injections
1964; American Medical Association; Volume: 11; Issue: 5 Linguagem: Inglês
10.1001/archneur.1964.00460230071006
ISSN1538-3687
Autores Tópico(s)Pain Mechanisms and Treatments
ResumoAlumina cream applications to brain and spinal cord have been carried out in several species of laboratory animals, being variously used to produce seizures 1,2 and other neurological manifestations. 3,4 The study most relevant to the present one is that of Kennard 5 who described a chronic sensory hyperirritability in cats produced by the lumbar intrathecal injection of alumina cream. She postulated that abnormal sensations developed at a discrete chronic injury but that spread of symptoms could occur to body parts not involved initially in the pathological process. In this regard, the condition bore a striking similarity to causalgia in man. Through the use of the stimulus-response techniques of neurophysiology, it is now possible to examine the form and distribution of evoked potentials at several levels of the nervous system. Such potentials can be evoked either by tactile or by nerve stimulation. To search for evoked potential changes subsequent to chronic
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