Bioactive Compounds from the Sea Hares of Two Genera: Aplysia and Dolabella
1997; Oxford University Press; Volume: 70; Issue: 7 Linguagem: Inglês
10.1246/bcsj.70.1479
ISSN1348-0634
AutoresKiyoyuki Yamada, Hideo Kigoshi,
Tópico(s)Neurobiology and Insect Physiology Research
ResumoAbstract This account describes the chemistry of the bioactive compounds isolated from the sea hares belonging to two genera: Aplysia and Dolabella. The bioactive compounds are classified as i) polyketides, ii) terpenes, iii) peptides and depsipeptides, and iv) others. Special emphasis is placed on the chemistry of cytotoxic compounds such as aplyronines and dolastatins that were obtained in our laboratory: Their isolation, structural elucidation, synthesis, and selected bioactivities data are summarized.
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