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BIBTEX RIS

Excesso de peso em pacientes submetidos ao transplante hepático

2013; Brazilian College of Surgeons; Volume: 40; Issue: 6 Linguagem: Inglês

10.1590/s0100-69912013000600014

1809-4546

Lucilene Rezende Anastácio, Michel Cardoso de Ângelis Pereira, Eduardo García Vilela, Agnaldo Soares Lima, María Isabel Toulson Davisson Correia,

Liver Disease and Transplantation

This review aims to describe the incidence and prevalence of overweight and obesity after liver transplantation and the consequences associated with it. Literature review consultation was conducted in Medline / PubMed, SciELO, EMBASE and LILACS, with the combination of the following keywords: liver transplantation, overweight, obesity, weight gain. Overweight is incident on more than 60% of patients undergoing liver transplantation and obesity rates exceed 20% in the first year after surgery, during which occurs the largest relative weight gain. Studies have shown that between 60% and 70% of patients undergoing liver transplantation are overweight after the third year, 90% with abdominal obesity. Associated factors are, among others, advanced age, family history of overweight and excess weight prior to liver disease. The contribution of immunosuppressive medication remains controversial. Some of the consequences of overweight are liver steatosis, steatohepatitis, diabetes mellitus, hypertension, dyslipidemia, cardiovascular disease and death.