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Artigo Revisado por pares
BIBTEX RIS

Veal heart ribonuclease P has an essential RNA component

1980; Elsevier BV; Volume: 96; Issue: 2 Linguagem: Inglês

10.1016/0006-291x(80)91430-8

ISSN

1090-2104

Autores

Eiko Akaboshi, Cecilia Guerrier-Takada, Sidney Altman,

Tópico(s)

RNA and protein synthesis mechanisms

Resumo

The activity of RNase P (EC 3.1.26.5) from veal heart can be abolished by pretreatment of the enzyme preparation with micrococcal nuclease, pancreatic RNase A, or RNase T1. This indicates that veal heart RNase P contains an RNA component essential for function of the enzyme as has also been shown for E. coli RNase P (1–3). Additionally, veal heart RNase P has a buoyant density in Cs2SO4 of 1.33 g/cm3, which is intermediate between that of protein and nucleic acid.

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