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The outcome of in vitro fertilization in advanced endometriosis with previous surgery: A case-controlled study

2003; Elsevier BV; Volume: 188; Issue: 2 Linguagem: Inglês

10.1067/mob.2003.13

1097-6868

Mohamed Aboulghar, Ragaa Mansour, Gamal I. Serour, Hesham Al-Inany, Mona M. Aboulghar,

Ovarian function and disorders

This study was undertaken to evaluate the outcome of in vitro fertilization (IVF) in patients with advanced pelvic endometriosis and previous surgical treatment.A case controlled study was performed.Patients with the diagnosis of stage IV endometriosis with previous surgical treatment were treated by IVF (group A = 85). An age-matched group of patients (group B = 177) with tubal factor infertility were treated with the same protocol of IVF. In group A, cycle cancellation because of poor response occurred in 29.7% compared with 1.1% in the control group (relative risk 26.03, 95% CI 6.02-112.45). There were 13 (15.3%) clinical pregnancies per stimulated cycle in group A compared with 93 (52.5%) clinical pregnancies in the control group, P <.0001 (odds ratio 0.29, 95% CI 0.15-0.55).The outcome of IVF in stage IV endometriosis with previous surgery was significantly lower compared with an age-matched group of tubal factor infertility.