Portal de Periódicos da CAPES

Nanomaterial-based cocaine aptasensors

2014; Elsevier BV; Volume: 68; Linguagem: Inglês

10.1016/j.bios.2014.12.052

1873-4235

Ahad Mokhtarzadeh, Ali Ezzati, Khalil Abnous, Miguel de la Guárdia, Mohammad Ramezani,

Molecular Sensors and Ion Detection

Up to now, many different methods have been developed for detection of cocaine, but most of these methods are usually time-consuming, tedious and require special or expensive equipment. Therefore, the development of simple, sensitive and rapid detection methods is necessary. In the last decade, aptamers have been used as a new biosensor platform for detection of cocaine in different samples. Aptamers are artificial single-stranded DNA or RNA oligonucleotides capable of binding to specific molecular targets with high affinity and if integrated to nanomaterials, it may lead in precise methods for cocaine detection in the common laboratories. In this review, recent advances and applications of aptamer-based biosensors and nanobiosensors, have been updated, paying attention to the use of fluorescence, colorimetric and electrochemical techniques for the detection and quantitative determination of cocaine.