THE KNOEVENAGEL CONDENSATION REACTION OF AROMATIC ALDEHYDES WITH MALONONITRILE BY GRINDING IN THE ABSENCE OF SOLVENTS AND CATALYSTS
2002; Taylor & Francis; Volume: 32; Issue: 22 Linguagem: Inglês
10.1081/scc-120014780
ISSN1532-2432
AutoresZhongjiao Ren, Weigud Cao, Weiqi Tong,
Tópico(s)Chemical Synthesis and Reactions
ResumoABSTRACT An improved Knoevenagel condensation reaction of aldehydes and malononitrile can be achieved by grinding at room temperature in the absence of solvents and catalysts. This process is simple, efficient, economical, and environmentally benign. Compared to reactions carried out by microwave irradiation, this procedure is completely free from organic solvents during both the reaction and separation of the product.
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