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Hypothyroid Graves' disease

1977; Elsevier BV; Volume: 62; Issue: 2 Linguagem: Inglês

10.1016/0002-9343(77)90325-4

1555-7162

James H. Christy, Richard S. Morse,

Growth Hormone and Insulin-like Growth Factors

Graves' disease has recently been shown to exist in a euthyroid form in untreated patients. Sporadic reports of a hypothyroid form are beginning to emerge, thus illustrating the multlfaceted nature of this disorder, with thyrotoxicosis at one end of the spectrum and hypothyroidism at the other. Three patients with nonthyrotoxic Graves' disease and concomitant hypothyroidism were seen at Emory University Hospital in one year, and detailed studies were made to help elucidate the nature of this unusual combination. Results of these studies are reported and briefly discussed. It is suggested that, until more is known about this intriguing aspect of the Graves' disease spectrum, the label “hypothyroid Graves' disease” is justifiable.