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Model for oxygen transfer in a shake flask

1978; Wiley; Volume: 20; Issue: 11 Linguagem: Inglês

10.1002/bit.260201102

1097-0290

J. C. van Suijdam, N. W. F. Kossen, A. C. Joha,

Viral Infectious Diseases and Gene Expression in Insects

Abstract The shake flask is a very common and useful tool for the study of submerged fermentations on a small scale. However, the oxygen supply may easily become a limiting factor. A model for the aeration in shake flasks is presented that enables one to predict whether in the course of an experiment the oxygen supply is becoming a growth‐limiting factor or not. The results of measurements of the transfer coefficient of a cotton plug and the oxygen mass‐transfer coefficient k l a are also given.