Peptide synthesis by a combination of solid-phase and solution methods III resin derivatives allowing minimum-racemization coupling of nα-protected amino acids
1989; Elsevier BV; Volume: 30; Issue: 48 Linguagem: Inglês
10.1016/s0040-4039(00)70665-4
ISSN1873-3581
AutoresM. Mergler, R. Nyfeler, Jacques Gosteli,
Tópico(s)Monoclonal and Polyclonal Antibodies Research
ResumoThe conversion of 4-alkoxy benzyl alcohol resin and 2-methoxy-4-alkoxy benzyl alcohol resin (SASRIN) into the corresponding halides is described. To these, Nα-protected amino acids can be coupled with minimal racemization.
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