Aerobic visible light-oxidation of aromatic methyl groups to carboxylic acids
2007; Springer Science+Business Media; Volume: 6; Issue: 5 Linguagem: Inglês
10.1039/b702703f
ISSN1474-9092
AutoresShin‐ichi Hirashima, Akichika Itoh,
Tópico(s)Chemical Synthesis and Reactions
ResumoA catalytic amount of magnesium bromide diethyl etherate (MgBr2.Et2O) enables us to carry out the aerobic photo-oxidation of a methyl group at the aromatic nucleus to the corresponding carboxylic acid in high yield under irradiation of VIS from a general-purpose fluorescent lamp. The bromine radical is thought to be generated in situ by continuous aerobic photo-oxidation of the bromine anion from MgBr2.Et2O, and to effect this oxidation reaction.
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