Portal de Periódicos da CAPES

Physicochemical Properties of 9-(Alkylsulfanyl)- and 9-(Arylsulfanyl)acridine Derivatives and Their Interaction with (2-Hydroxypropyl)cyclodextrins

2006; Wiley-VCH; Volume: 71; Issue: 2 Linguagem: Inglês

10.1135/cccc20060179

1212-6950

I. Němcová, Karel Nesměrák, Božena Kafková, Jan Sejbal,

Crystallization and Solubility Studies

Acid-base properties and aggregations of 9-(alkylsulfanyl)- and 9-(arylsulfanyl)acridine derivatives were studied as a part of systematic study of physicochemical properties of these compounds synthesized as potential drugs. The effect of the (2-hydroxypropyl)cyclodextrins on these properties and their association with the acridines was also followed.